dc.contributor.advisor | Juliandi, Berry | |
dc.contributor.advisor | Boediono, Arief | |
dc.contributor.advisor | Sasai, Noriaki | |
dc.contributor.author | Christin, Nia | |
dc.date.accessioned | 2019-01-16T06:57:10Z | |
dc.date.available | 2019-01-16T06:57:10Z | |
dc.date.issued | 2018 | |
dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/95563 | |
dc.description.abstract | Adolescence is a sensitive period when neurogenesis rate is increases.
Chronic stress that occurs during adolescence can cause a long-term effects on
adult behavior and morphology of hippocampus. Light-dark transition test showed
that CUS successfully produced depressed adolescent mice. Y-alternation test
revealed that short-term effect of CUS improved spatial memory in mice,
resembled the capability of non-stressed adult while cell counting performed with
HE staining did not showed a significant effect on proliferation, cell maturing, and
cell survival in DG. Complexity of dendrites in DG and pyramidal neurons of
CA1 performed using Golgi-Cox staining. Apical dendrites of DG did not showed
a significant effect of CUS on dendritic complexity of DG. In contrast, both of
apical and basal dendrites of CA1 showed a significant short-term effect of CUS,
seen from the number of intersections. Maximum dendritic span and total
dendritic length did not show a significant differences. It is remarkable that both
short and long-term effect of CUS is changes the complexity of CA1 pyramidal
neuron and transciently increases spatial memory on adolescent mice. | id |
dc.language.iso | en | id |
dc.publisher | Bogor Agricultural University (IPB) | id |
dc.subject.ddc | Biology | id |
dc.subject.ddc | Golgi Zone | id |
dc.subject.ddc | 2018 | id |
dc.subject.ddc | Bogor-Jawa Barat | id |
dc.title | The Consequences of Chronic Unpredictable Stress Exposure to Spatial Memory of Adolescent Mice (Mus musculus albinus). | id |
dc.type | Undergraduate Thesis | id |
dc.subject.keyword | chronic unpredictable stress | id |
dc.subject.keyword | dendritic complexity | id |
dc.subject.keyword | Golgi-Cox | id |
dc.subject.keyword | neurogenesis | id |
dc.subject.keyword | spatial memory | id |