The use of delayed implantation model in the study of hormonal requirement for implantation in the rat

Abstract

a delayed implantation rat model has been developed. Methode of ovariectomy was described. Ovaiectomy be performed up to the morning of day 4, beyond that ovariectomy was not effective. Injection of Tamoxifen (10 or 50 ug/200 g BW) in the afternoon of either day 4 or day 5 inhibited impantation.