| dc.contributor.advisor | Syaefudin | |
| dc.contributor.advisor | Enggarini, Wening | |
| dc.contributor.author | Mukti, Seliani Fitria | |
| dc.date.accessioned | 2024-07-15T11:58:01Z | |
| dc.date.available | 2024-07-15T11:58:01Z | |
| dc.date.issued | 2024 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/153689 | |
| dc.description.abstract | Infeksi jamur, seperti kandidiasis oleh Candida albicans dan aspergillosis oleh Aspergillus flavus, dapat merugikan dan menurunkan kualitas kesehatan manusia. Salah satu sumber yang diduga mengandung senyawa aktif antijamur adalah kayu ulin karena dikenal sebagai kayu kelas kuat, awet, dan tahan jamur. Penelitian ini bertujuan menentukan aktivitas antijamur ekstrak etanol kayu ulin (E. zwageri) dari berbagai aksesi asal Kalimantan dalam menghambat pertumbuhan jamur A. flavus dan C. albicans. Kayu ulin yang digunakan terdiri dari 10 aksesi, yaitu IX.C.10, IX.C.130, IX.C.7, IX.C.8, IX.D.125A, IX.D.130, IX.D.191, V.E.34, VIII.G.207, dan XVII.I.97. Pengujian aktivitas antijamur dilakukan dengan metode difusi cakram. Hasil penelitian menunjukkan bahwa kisaran nilai diameter zona bening dari 10 aksesi kayu ulin sebesar 4.22-18.72 mm dan 2.36-11.50 mm, berturut-turut untuk penghambatan terhadap C. albicans dan A. flavus. Aksesi VIII.G.207 memiliki daya aktivitas antijamur tertinggi sebesar 18.72±0.26 mm (C. albicans) dan 11.50±0.12 mm (A. flavus). Analisis lanjut menunjukkan bahwa aksesi ini memiliki Konsentrasi Hambat Minimum (KHM) sebesar 1.94±0.17 mm (C. albicans) dan 2.36±0.40 mm (A. flavus) pada konsentrasi 250 ppm. | |
| dc.description.sponsorship | Fungal infections, such as candidiasis by Candida albicans and aspergillosis by Aspergillus flavus, can be detrimental and reduce the quality of human health. One source that is thought to contain active antifungal compounds is ironwood because it is known as a class of wood that is strong, durable and fungal-resistant. This study aimed to determine the antifungal activity of ethanol extract of ironwood (E. zwageri) from various accessions from Kalimantan in inhibiting the growth of the fungi A. flavus and C. albicans. The ironwood used consists of 10 accessions, namely IX.C.10, IX.C.130, IX.C.7, IX.C.8, IX.D.125A, IX.D.130, IX.D. 191, V.E.34, VIII.G.207, and XVII.I.97. Antifungal activity testing was carried out using the disc diffusion method. The results showed that the clear zone diameter values range for 10 ironwood accessions was 4.22-18.72 mm and 2.36-11.50 mm, respectively, for inhibition of C. albicans and A. flavus. Accession VIII.G.207 had the highest antifungal activity of 18.72 ± 0.26 mm (C. albicans) and 11.50 ± 0.12 mm (A. flavus). Further analysis showed that this accession had a Minimum Inhibitory Concentration (MIC) of 1.94 ± 0.17 mm (C. albicans) and 2.36 ± 0.40 mm (A. flavus) at a concentration of 250 ppm. | |
| dc.language.iso | id | |
| dc.publisher | IPB University | id |
| dc.title | Aktivitas Antijamur Ekstrak Etanol Kayu Ulin (Eusideroxylon zwageri) dari Berbagai Aksesi Asal Kalimantan | id |
| dc.title.alternative | | |
| dc.type | Skripsi | |
| dc.subject.keyword | antifungal | id |
| dc.subject.keyword | Aspergillus flavus | id |
| dc.subject.keyword | Candida albicans | id |
| dc.subject.keyword | ironwood | id |
