The morphological of fetal lung of doe injected with PMSG hormon prior mating.
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Date
2019Author
Tria Amanda, Rahmitha
Winarto, Adi
Manalu, Wasmen
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PMSG hormone is one of the reproductive hormones that play a role in
determining embryonic and fetal development during the pregnancy period. The
report shows that PMSG hormone able to improve the parent's hormonal conditions
during the pregnancy period by triggering an increase of follicles number and the
corpus luteum. The information on the effect of PMSG hormone to the mother prior
mating in order to improve hereditary quality in general is still lacking, particular
to the fetal lung development. This study was designed to evaluate the
morphological development of the lung fetal, which delivered by PMSG hormone
induced doe. The evaluation of lung tissues was carried out on three fetal lungs,
which were from control doe without PMSG induction (IN), PMSG induced doe
(7,5 IU/kg BW/IP7,5), and PMSG induced doe in dose of (15 IU/kg BB /IP15). The
lung tissue samples were processed by histological method and stained by
Hematoxylin Eosin (HE) staining then measured its pleura thickness, bronchus
diameter, and the diameter of alveolus. The analysis was done using a t-test on
Microsoft Excel. The results of the study showed that anatomically the lungs were
fully developed which showed a complete lobe formation. Histological image also
showed that the development of the respiratory system of the alveolar duct, alveolar
sac, and fetal alveol has developed larger in the IP fetus than the IN fetus. In
conclusion, the injection of PMSG hormone in the mother goat can accelerate the
development of parts of the lungs that can be seen in the tip of bronchial gland and
the IP fetal lungs growing larger than the fetus IN.