Sintesis 3-Benzoil-7-hidroksiflavon dari Resorsinol

dc.contributor.advisor	Arifin, Budi
dc.contributor.advisor	Achmadi, Suminar Setiati
dc.contributor.author	Solovky, Dwi Artha
dc.date.accessioned	2013-03-20T07:10:39Z
dc.date.available	2013-03-20T07:10:39Z
dc.date.issued	2013
dc.identifier.uri	http://repository.ipb.ac.id/handle/123456789/61501
dc.description.abstract	Flavonoid is the most abundant naturally-occuring polyphenolic compound with C6-C3-C6 carbon skeleton. Flavones is a group of flavonoid having a broad bioactivity spectrum. In this experiment, 3-benzoyl-7-hydoxyflavone was successfully synthesized via 2-steps from resorcinol. In the first step, resorcinol was acetylated with AcOH/ZnCl2 producing resacetophenone with 89% yield. Subsequently, benzoylation and rearrangement of resacetophenone using 2 equivalent of benzoyl chloride and 7 equivalent of K2CO3 in acetone produced 3-benzoyl-7-hydroxyflavone with 62% yield. Synthesis of 3-benzoyl-7-hydroxyflavone from resorcinol provided evidence for new reaction mechanism of flavon formation without Baker-Venkataraman rearrangement proposed by several previous researchers. All products in this study has been characterized spectroscopically.	en
dc.subject	Bogor Agricultural University (IPB)	en
dc.subject	resacetophenone.	en
dc.subject	flavone	en
dc.subject	benzoylation	en
dc.title	Sintesis 3-Benzoil-7-hidroksiflavon dari Resorsinol	en