Profil Darah Domba Garut Pasca Pemasangan Implan Hormon Intravaginal

Abstract

Penggunaan implan hormon intravaginal merupakan salah satu metode sinkronisasi estrus pada ternak, namun informasi mengenai biokompatibilitas sistemiknya masih terbatas. Penelitian ini bertujuan menganalisis profil darah dan mengevaluasi dampak fisiologis pemasangan implan hormon intravaginal pada domba Garut. Sebanyak 10 ekor domba Garut betina dibagi ke dalam lima kelompok perlakuan, yaitu CIDR, plasebo, Single-hormone, Double-hormone, dan Multi-hormone. Sampel darah dikoleksi sebelum implantasi, selama implantasi, dan setelah eksplantasi, kemudian dianalisis menggunakan hematology analyzer. Data dianalisis dengan Repeated Measures ANOVA. Sebagian besar parameter hematologi berada dalam rentang fisiologis normal. Perubahan signifikan ditemukan pada MCV, MCHC, RDW, trombosit, PCT, P-LCR, dan persentase neutrofil, tanpa disertai gangguan klinis maupun indikasi respons penolakan sistemik. Implan hormon intravaginal menunjukkan biokompatibilitas yang baik dan relatif aman digunakan pada domba.

Intravaginal hormone implants are widely used for estrus synchronization in livestock, but their biocompatibility requires further evaluation. This study analyzed blood profiles and physiological responses to intravaginal hormone implantation in Garut sheep. Ten female Garut sheep were assigned to five treatment groups: CIDR, placebo, Single-hormone, Double-hormone, and Multi-hormone. Blood samples were collected before implantation, during implantation, and after explantation and analyzed using a hematology analyzer. Data were analyzed using Repeated Measures ANOVA. Most hematological parameters remained within normal physiological ranges. Significant changes were observed in MCV, MCHC, RDW, platelet count, PCT, P-LCR, and neutrophil percentage, without clinical abnormalities or evidence of systemic rejection. These findings indicate that intravaginal hormone implants have good biocompatibility and are relatively safe for use in Garut sheep.