| dc.contributor.advisor | Arif, Zulhan | |
| dc.contributor.advisor | Batubara, Irmanida | |
| dc.contributor.author | Ekawati, Mella | |
| dc.date.accessioned | 2024-11-14T23:33:00Z | |
| dc.date.available | 2024-11-14T23:33:00Z | |
| dc.date.issued | 2024 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/159472 | |
| dc.description.abstract | Produk penolak nyamuk umumnya mengandung senyawa aktif sintetik yang
dapat membahayakan jika digunakan secara berlebihan pada kadar tinggi dan tidak
mematuhi instruksi pada label produk. Senyawa para-mentana-3,8-diol (PMD)
merupakan salah satu alternatif bahan aktif penolak nyamuk dengan efek
perlindungan yang sebanding dengan N,N-dietil-3-metilbenzamida (DEET). PMD
dapat disintesis melalui reaksi siklisasi intramolekuler sitronelal yang dikatalisis
oleh asam. Penelitian ini mengkaji pengaruh suhu, konsentrasi asam, dan waktu
reaksi pada rendemen dan selektivitas pembentukan PMD. Hasilnya menunjukkan
kondisi reaksi optimum pada suhu 70 °C, konsentrasi asam sulfat 0,25%, dan waktu
reaksi 5 jam, menghasilkan rendemen PMD 90,60%, konversi sitronelal 98,44%,
dan selektivitas PMD 92,04%. Karakterisasi menggunakan GC-MS dan FTIR serta
uji sifat fisikokimia juga mengonfirmasi keberhasilan pembentukan senyawa PMD.
Kata kunci: penolak nyamuk, PMD, reaksi siklisasi intramolekuler, sitronelal | |
| dc.description.abstract | Mosquito-repellent products generally contain synthetic active compounds
that can be harmful if used excessively at high levels and do not comply with the
instructions on the product label. para-Mentane-3,8-diol (PMD) compound is one
of the alternative mosquito-repellent active ingredients with a protective effect
comparable to N,N-diethyl-3-methylbenzamide (DEET). PMD can be synthesized
through a citronellal intramolecular cyclization reaction catalyzed by acids. This
study examines the influence of temperature, acid concentration, and reaction time
on the yield and selectivity of PMD formation. The results showed optimal reaction
conditions at 70 °C, sulfuric acid concentration of 0.25%, and reaction time of 5
hours, resulting in PMD yield of 90.60%, citronellal conversion of 98.44%, and
selectivity of PMD of 92.04%. Characterization using GC-MS and FTIR, as well
as physicochemical properties tests, also confirmed the success of the formation of
PMD compounds.
Keywords: mosquito-repellent, PMD, intramolecular cyclization reaction,
citronellal | |
| dc.description.sponsorship | PT Alam Indonesia Raharja | |
| dc.language.iso | id | |
| dc.publisher | IPB University | id |
| dc.title | Optimasi Suhu, Waktu, dan Konsentrasi Asam Sulfat dalam Sintesis para-Mentana-3,8-diol dari Minyak Sitronelal | id |
| dc.title.alternative | Optimization of Temperature, Time, and Concentration of Sulfuric Acid in the Synthesis of Para-Mentane-3,8-Diol from Citronellal Oil | |
| dc.type | Skripsi | |
| dc.subject.keyword | mosquito-repellent | id |
| dc.subject.keyword | PMD | id |
| dc.subject.keyword | intramolecular cyclization reaction | id |
| dc.subject.keyword | citronellal | id |
