| dc.description.abstract | This research was purposed to analyze potency of angkak on hematological parameters and organs recovery in quinine induced rat. Rats were randomly divided into five groups. Group I were given orally aquades, group II received 100 g/kg bb quinine 14 day afterward not received angkak, group III received 100 g/kg bb quinine 14 day afterward received 0.04 g/kg bb angkak 14 day, group IV received 100 g/kg bb quinine afterward received 0.08 g/kg bb angkak, and group V not received quinine afterward received 0.04 g/kg bb angkak. Hematology analysis measured every 3 day. At 29 th day, the rats were necropsied to see the lesion on the liver and kidney both macroscopically and microscopically. The treatment with angkak can increasing the body weight of the rats (p<0.05). Analysis result of platelet showed that treatment using 0.04 g/kg bb angkak able to increase the sum of platelets (p<0.05). The treatment using angkak have not demonstrated significantly effect on red blood cell, hemoglobin, and hematocrit (p>005). Observation histopathology of the test animals liver and kidney showed the treatment using 0.04 g/kg bb and 0.08 g/kg bb angkak was confirmed helping the liver and kidney to recover from histopathology lesion caused negative effect. Statistical analysis result showed that recover using angkak is differently significant. | id |
