| dc.contributor.advisor | Gunanti | |
| dc.contributor.advisor | Rahminiwati, Min | |
| dc.contributor.author | Ngaini, Hesti Nur | |
| dc.date.accessioned | 2022-10-21T08:49:07Z | |
| dc.date.available | 2022-10-21T08:49:07Z | |
| dc.date.issued | 2022-10-21 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/115053 | |
| dc.description | Stem cells are able to differentiate into any cell types and suitable for target
organs, so they have the potential as alternative in the treatment of myocardial
infarction. Thoracotomy and stem cell patch require minimal invasive condition
and stability of heart. The purpose of this research was to examine the effect of
pAEC on body temperature, heart rate, and respiration rate of pigs (Sus scrofa
domestica) during myocardial infarction surgery. Four local pigs were 2 males dan
2 females. All pigs were given pAEC (porcine Amniotic Epithelial Cells) after
infarction. Anesthetics were given same: ketamine 10% dose 20 mg/kg BW (IM),
xylazine 2% dose 2 mg/kg BW (IM), atropine sulfate 0,3% dose 0.5 – 1 mL/50kg
BW (IV), propofol 4 mg/kg BW (IV), fentanyl 0.02 – 0.05 mg/kg/BW (IV), and
inhalation anesthetics (isoflurane). The measured variables from parenteral
anesthetics were body temperature, heart rate, and respiration rate. The results
showed that there was no significant difference (Duncan: P > 0,05) in heart rate,
respiration rate, and body temperature with pAEC intervention in myocardial
infarction surgery. | id |
| dc.description.abstract | Sel punca sebagai sel yang mampu berdiferensiasi menjadi jenis sel yang sesuai
dengan organ target sehingga berpotensi untuk dikembangkan sebagai alternatif
pada penanganan infark miokardium, Thoracotomy dan aplikasi patch sel punca
membutuhkan kondisi minimal invasif dan kestabilan kondisi jantung. Penelitian
ini bertujuan menguji pengaruh tindakan operasi infak miokardium yang diberikan
pAEC terhadap temperatur tubuh, frekuensi jantung, dan respirasi babi. Empat babi
lokal yang digunakan terdiri dari 2 ekor jantan dan 2 ekor betina. Semua babi
diberikan pAEC (porcine Amniotic Epithelial Cells) setelah terbentuk infark
miokardium. Anestetikum yang diberikan sama, berupa ketamin 10% dosis 20
mg/kg BB (IM), xylazin 2% dosis 2 mg/kg BB (IM), atropin sulfat 0,3% dosis 0,5
– 1 mL/50 kg BB (IV), propofol 4 mg/kg BB (IV), fentanil 0,02 – 0,05 mg/kg BB
(IV), dan anestesi inhalasi (isofluran). Variabel yang diamati adalah temperatur
tubuh, frekuensi jantung, dan respirasi. Hasil penelitian menunjukkan bahwa tidak
terdapat perbedaan signifikan (Duncan: P > 0,05) pada temperatur tubuh, frekuensi
jantung, dan respirasi dengan intervensi pAEC pada tindakan operasi infark
miokardium. | id |
| dc.language.iso | id | id |
| dc.publisher | IPB University | id |
| dc.title | Pengaruh Tindakan Operasi dengan Intervensi pAEC Terhadap Temperatur, Frekuensi Jantung dan Respirasi Babi | id |
| dc.title.alternative | Effect of pAEC Intervention on Myocardial Infarction Surgery in Pigs Temperature, Heart and Respiration Rate | id |
| dc.type | Undergraduate Thesis | id |
| dc.subject.keyword | babi | id |
| dc.subject.keyword | infark miokardium | id |
| dc.subject.keyword | pAEC | id |
| dc.subject.keyword | tindakan operasi | id |
| dc.subject.keyword | indonesian local pig | id |
| dc.subject.keyword | infarct myocardium | id |
| dc.subject.keyword | surgery action | id |
