| dc.contributor.advisor | Iswantini, Dyah | |
| dc.contributor.advisor | Wahyuni, Wulan Tri | |
| dc.contributor.author | Hayati, Nurjannah | |
| dc.date.accessioned | 2022-08-31T05:43:04Z | |
| dc.date.available | 2022-08-31T05:43:04Z | |
| dc.date.issued | 2022 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/114233 | |
| dc.description.abstract | Artritis gout (asam urat) adalah penyakit gangguan sendi. Pencegahan gout
dapat dilakukan dengan cara memberikan obat-obatan yang bekerja langsung
pada enzim yang berperan meningkatkan kadar asam urat yaitu xantina oksidase.
Penghambatan xantina oksidase terjadi oleh alopurinol. Penelitian bertujuan
meninjau berbagai tulisan mengenai potensi beberapa ekstrak tanaman herbal
sebagai inhibisi terhadap xantina oksidase untuk mengetahui potensinya sebagai
anti gout (asam urat). Metode yang digunakan adalah menelaah pustaka primer
berbagai tulisan, berupa jurnal, berita, makalah, skripsi, tesis, dan disertasi. Hasil
penelitian menunjukan terdapat beberapa tanaman herbal yang memiliki senyawa
aktif seperti flavonoid yang mampu menjadi inhibitor bagi xantina oksidase.
Tanaman tersebut di antaranya, sidaguri, tempuyung, daun salam, daun alpukat,
daun jarum tujuh bilah, dan keladi candik. Tanaman-tanaman tersebut memiliki
potensi yang baik dalam menghambat xantina oksidase. Hal ini dapat dilihat dari
nilai aktivitas inhibisinya yang lebih tinggi dari alopurinol | id |
| dc.description.abstract | Gout artritis (uric acid) is a disease of joint disorders. Prevention of gout
can be done by giving drugs that work directly on enzymes that play a role in
increasing uric acid levels, is xanthine oxidase. Allopurinol is inhibited by
xanthine oxidase. This study aims to review various articles on the potential of
several herbal plant extracts as xanthine oxidase inhibitors to determine their
potential as anti-gout. The method used is a literature review for the primary
literature of various kinds of writings, in the form of journa ls, news, papers,
theses, and dissertations. The results showed that there were several herbal plants
that had active compounds such as flavonoids which were able to become
inhibitors of xanthine oxidase. These plants include sidaguri, tempuyung, bay
leaves, avocado leaves, jarum tujuh bilah leaves, and keladi taro. These plants
have good potential in inhibiting xanthine oxidase. This can be seen from the
value of its inhibitory activity which is better than alopurinol. | id |
| dc.language.iso | id | id |
| dc.publisher | IPB University | id |
| dc.title | Kajian Potensi Beberapa Ekstrak Tanaman Herbal sebagai Anti Asam Urat dan Aktivitas Inhibisinya terhadap Xantina Oksidase | id |
| dc.type | Undergraduate Thesis | id |
| dc.subject.keyword | gout | id |
| dc.subject.keyword | alopurinol | id |
| dc.subject.keyword | herbal plants | id |
| dc.subject.keyword | inhibition. | id |
