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      Parameter Uji Dalam Pendekatan Diagnosis Cholangiohepatitis pada Anjing di Praktik Drh. Setyo Widodo, dkk.

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      Date
      2022-01-03
      Author
      Satvika, Fadhila
      Widodo, Setyo
      Winarto, Adi
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      Abstract
      Cholangiohepatitis merupakan suatu inflamasi yang terjadi disekitar kantung empedu dan meluas ke area parenkim hati. Tujuan dari studi ini adalah mengidentifikasi parameter uji pada anjing yang menderita cholangiohepatitis berdasarkan gejala klinis, hasil hematologi, dan hasil pemeriksaan fungsi hati. Studi dilakukan menggunakan data sekunder lima ekor anjing dari klinik Praktik Drh Setyo Widodo, dkk., di Bogor. Data diambil berdasarkan hasil pemeriksaan fisik, uji hematologi, dan fungsi hati yang diinterpretasikan mengarah ke cholangiohepatitis. Hasil pemeriksaan fisik melalui anamnesa dan temuan klinis tidak menunjukan hasil signifikan untuk cholangiohepatitis. Sedangkan hasil uji hematologi terhadap cholangiohepatitis menunjukan anjing Pasien 3 dan Pasien 5 mengalami anemia, anjing Pasien 2 dan Pasien 4 mengalami trombositopenia anjing Pasien 2, Pasien 3, dan Pasien 5 mengalami peningkatan LED, dan kelima anjing mengalami leukositosis. Berdasarkan uji fungsi hati terjadi peningkatan pada aktivitas enzim hati, GGT (gamma glutamyl transferase) dan ALP (alkaline phosphatase) di Pasien 1 dan Pasien 2, peningkatan GGT di Pasien 3, dan peningkatan GOT (glutamic oxeloacetic transaminase), GPT (glutamic pyruvic transaminase), GGT dan ALP di Pasien 4 dan Pasien 5. Pendekatan diagnosis cholangiohepatitis dapat diketahui berdasarkan peningkatan kadar enzim GGT yang secara variatif didukung peningkatan kadar enzim hati lainnya (ALP, GPT, GOT), serta kondisi hematologi berupa leukositosis.
       
      Cholangiohepatitis is an inflamation that occurs around the gallbladder and extend toward the liver parenchyma area. This study aims to identify the parameter test for cholangiohepatitis cases in dogs based on clinical symptoms, hematology test, and liver function test. This study used secondary data from five dogs provided by Praktik Drh. Setyo Widodo, dkk., clinic in Bogor. Data were taken based on physical examination, hematology test, and liver function test. The result wasn’t significant for cholangiohepatitis based on physical examination through anamnesis and clinical findings. While based on hematology test for cholangiohepatitis shows, Patient 3 and Patient 5 had anemia, Patient 2 and Patient 4 had thrombocytopenia, Patien 2, Patient 3, and Patient 5 had increase of ESR, and all five dogs have leukocytosis. Liver function test shows an increase of liver enzymes activity, GGT (gamma glutamyl transferase) and ALP (alkaline phosphatase) in Patient 1 and Patient 2, GGT in Patient 3, and GOT (glutamic oxeloacetic transaminase), GPT (glutamic pyruvic transaminase), GGT, and ALP in Patient 4 and Patient 5. The approach to the diagnosis of cholangiohepatitis can be identify based on the increased levels of GGT enzyme and variously supported by increased of other liver enzymes (ALP, GPT, GOT), as well as hematological condition such as leukocytosis.
       
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      http://repository.ipb.ac.id/handle/123456789/110436
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      • UT - Veterinary Clinic Reproduction and Pathology [2186]

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      Indonesia DSpace Group 
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