| dc.contributor.advisor | Mas'ud, Zainal Alim | |
| dc.contributor.author | Fadhilah, Fathimah Himmah | |
| dc.date.accessioned | 2021-11-04T05:55:10Z | |
| dc.date.available | 2021-11-04T05:55:10Z | |
| dc.date.issued | 2021 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/109807 | |
| dc.description.abstract | Senyawa fatty acid ester of hydroxy fatty acid (FAHFA) merupakan senyawa turunan lipid yang ditemukan pada tahun 2014 dalam jaringan adiposa mencit. Struktur dari senyawa yang diketahui memiliki aktivitas antidiabetes dan antiinflamasi tersebut terdiri atas rantai asam lemak dan hidroksi asam lemak. Sintesis berbagai kelompok senyawa FAHFA telah banyak diupayakan. Material awal yang dapat digunakan dalam jalur sintesis senyawa tersebut antara lain senyawa aldehida, epiklorohidrin, bentuk enol dan alkuna, α,ω-diol, dan metil ester asam lemak. Material awal perlu dipilih berdasarkan kelompok dan jenis regioisomer dari senyawa FAHFA yang akan disintesis. Hasil karakterisasi senyawa menggunakan spektroskopi inframerah dan resonans magnetik inti menunjukkan sinyal khas dari gugus karboksilat serta ikatan ester yang menghubungkan dua rantai asam lemak penyusun. Sinyal khas lain yang berasal dari gugus olefin terdapat pada senyawa FAHFA dengan rantai takjenuh. | id |
| dc.description.abstract | The fatty acid ester of hydroxy fatty acid (FAHFA) compound is a lipid derivative compound that was discovered in 2014 in the adipose tissue of mice. The structure of the compound which is known to have antidiabetic and anti-inflammatory activity consists of fatty acid and hydroxy fatty acid chains. Many attempts have been made to synthesize various groups of FAHFA compounds. The starting materials that can be used in the synthesis pathway of these compounds include aldehydes, epichlorohydrin, enol, and alkyne forms, diols, and fatty acid methyl esters. The starting material needs to be selected based on the group and type of regioisomer of the FAHFA compound to be synthesized. The results of the characterization of compounds using infrared spectroscopy and nuclear magnetic resonance showed a typical signal from the carboxylate group and the ester bond connecting the two constituent fatty acid chains. Another characteristic signal from the olefin group is found in FAHFA compounds with unsaturated chains | id |
| dc.language.iso | id | id |
| dc.publisher | IPB University | id |
| dc.title | Studi Pustaka Sintesis Senyawa Fatty Acid Ester of Hydroxy Fatty Acid (FAHFA) dan Karakterisasinya | id |
| dc.title.alternative | Literature Study on the Synthesis of Fatty Acid Ester of Hydroxy Fatty Acid (FAHFA) and Their Characterizations | id |
| dc.type | Undergraduate Thesis | id |
| dc.subject.keyword | FAHFA | id |
| dc.subject.keyword | fatty acid ester of hydroxy fatty acid | id |
| dc.subject.keyword | lipid | id |
| dc.subject.keyword | synthesis | id |
