Characterization of Biphasic Calcium Phosphate with Ratio of 70/30 Before and After Implanted into Sheep’s Bone

Abstract

Nowadays, biphasic calcium phosphate is used for biomaterial to cure bone damage. This study focuses only on mixing ratio of 70% mass of hydroxyapatite and 30% mass of tricalcium phosphate with chitosan and acetic acid as the hardening. Pure HA had done by wet precipitation in sintering process at temperature of 900 oC while β-TCP is at temperature of 1000 oC. Mechanical method of BCP is proven to be a non toxic material and could absorb by the mineral body. Implanted BCP was characterized with XRD, FTIR, SEM-EDS and bone characterization with Vickers Hardness. In XRD analysis, the result is adding chitosan makes BCP less accuracy of pure HA and β-TCP. FTIR shows composition of BCP sample with HA, TCP, H2O, AKB, and N-H bending. SEMEDS releases ratio Ca/P of implant in post operation has irregularity caused by interaction with bone that supported by Vickers Hardness number. HV for 1 month of post operation have larger number for both implanted and control bone.