Aplikasi Eritromisin dan Kloramfenikol dalam Menekan Jumlah Campylobacter spp. dan Koliform pada Ayam yang Diinfeksi oleh Campylobacter jejuni

Abstract

Campylobacter is one of the major pathogenic bacteria causing food poisoning that can be transmitted through poultry products. Infection C. jejuni and coliform in humans can be caused by eating contaminated food. Transmission can be achieved at the farm level with treatment suffering from campylobacteriosis in poultry, for example by administering antimicrobial. The aimed of this study was to determine the number of Campylobacter spp. and coliform in chickens were infected by C. jejuni before and after treatment with erythromycin and chloramphenicol. A total of 17 chickens kept divided into four experimental groups, namely (A) negative control, chickens were not infected by C. jejuni and without antibiotic treatment, (B) positive control, chickens were infected by C. jejuni and without antibiotic treatment, (C) chickens were infected by C. jejuni and were treated by erythromycin, and (D) chickens infected by C. jejuni and treated by chloramphenicol. Inspection was done in three times, in one day old chickens, after infection (12 days old chickens), and after treatment (17 days old chickens). The average number of Campylobacter spp. at one day old chickens was 2.0 + 0.57 MPN/g, while the average number of coliforms was 2.8 x 107 + 3.5 x 106 cfu/g. After was infected by C. jejuni, the average number of Campylobacter spp. increased to 46 + 27.15 MPN/g, while the average number of coliforms was 2.0 x 106 + 1.7 x 105 cfu/g. After treatment by erythromycin and chloramphenicol, the average number of Campylobacter spp. in both groups decreased, respectively 2.5 + 2.12 as MPN/g and 2 + 0 MPN/g, while the average number of coliforma much as 5.7 x 108 + 3.2 x 107 cfu/g and 4.3 x 108 + 1.7 x 108 cfu/g. From this research, erythromycin or chloramphenicol were effective for treatment of campylobacteriosis in chickens.