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Improvements of aged hippocampus functions by improvement of glutathione levels in rats supplemented with Alanine-Glutamine Dipeptide

Perbaikan fungsi pada penuaan hipokampus tikus yang diperantarai glutation dengan pemberian Dipeptida Alanil-Glutamina

dc.contributor.advisorManalu, Wasmen
dc.contributor.advisorKusumorini, Nastiti
dc.contributor.advisorAgungpriyono, Dewi Ratih
dc.contributor.authorSunarno
dc.date.accessioned2012-11-06T03:33:44Z
dc.date.available2012-11-06T03:33:44Z
dc.date.issued2012
dc.identifier.urihttp://repository.ipb.ac.id/handle/123456789/58377
dc.description.abstractIncreased age or oxidative stress decreases the function of the hippocampus. One way to improve the function of the aging hippocampus is to increase the level of glutathione in the hippocampus. Alanine-glutamine dipeptide experiment was designed to obtain the optimum concentrations of alanine glutamine dipeptide supplementation that can increase the levels of glutathione in the hippocampus, to obtain an improvement of histo morphology, mitocondrial structure, learning memory and motor activity ability, concrentations of alanine glutamine dipeptide in the plasma or the hippocampus after administration of 7 % alanine glutamine dipeptide, both in physiological aging or oxidative stress rats.en
dc.publisherIPB (Bogor Agricultural University)
dc.subjectalanine-glutamine dipeptideen
dc.subjectglutathioneen
dc.subjecthisto-morphologyen
dc.subjectmitochondrialen
dc.subjectagingen
dc.subjectoxidative stressen
dc.subjecthippocampus functionen
dc.titleImprovements of aged hippocampus functions by improvement of glutathione levels in rats supplemented with Alanine-Glutamine Dipeptideen
dc.titlePerbaikan fungsi pada penuaan hipokampus tikus yang diperantarai glutation dengan pemberian Dipeptida Alanil-Glutamina


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