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      Pemberian Susu Kedelai Fermentasi pada Tikus Putih (Rattus norvegicus) Bunting atau Menyusui terhadap Kinerja Reproduksi Anak Jantan

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      Date
      2012
      Author
      Sari, Oktipa
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      Abstract
      Fermented soy milk are the product of soybean which contain phytoestrogen. This study aims to analyses the effect of fermented soy milk on male offspring reproductive performance using rats as experimental animals. Twelve pregnant female rats were divided into four treatment groups: control (K), the groups was treated by fermented soy milk 4.99 gr/kg BW/day in volume 4 ml at 2nd until 11th day of pregnancy (A), 12th until 21st day of pregnancy (B), and 2nd until 11th day of lactation (C). Parameters observed were pregnant duration, number of pups, anogenital distance, body weight, testicular weight, testosteron level, and total sperm. Data were analyzed by Analysis of Variance (ANOVA) and continued by Duncan test with 95% ( =0.05) confidence interval. The result of this study indicated that the treatment of fermented soy milk at 2nd until 11th day of pregnancy, 12th until 21st day of pregnancy, or 2nd until 11th day of lactation showed lower testicular weight and testosteron level than non treatment group at 42th day old male offspring.
       
      Susu kedelai fermentasi merupakan produk olahan kedelai yang mengandung sejumlah fitoestrogen. Penelitian dilakukan untuk menganalisa pengaruh pemberian susu kedelai fermentasi terhadap kinerja reproduksi anak jantan dengan menggunakan tikus sebagai hewan percobaan. Sebanyak 12 ekor tikus betina bunting dibagi menjadi 4 kelompok, yaitu kelompok kontrol (K), kelompok yang diberi susu kedelai fermentasi 4.99 gr/kg BB/ hari dalam volume 4 ml pada usia kebuntingan 2 sampai dengan 11 hari (A), 12 sampai dengan 21 hari (B), dan masa laktasi 2 sampai dengan 11 hari (C). Parameter yang diukur adalah lama kebuntingan induk, jumlah anak sekelahiran, rataan bobot badan lahir anak, celah anogenital, bobot badan, bobot testis, kadar testosteron, dan jumlah sperma. Data dianalisis dengan menggunakan metode analisa sidik ragam (ANOVA) dan dilanjutkan dengan uji Duncan dengan selang kepercayaan 95% (α=0.05). Hasil penelitian pemberian susu kedelai fermentasi pada usia kebuntingan 2 sampai dengan 11 hari, 12 sampai dengan 21 hari, atau masa laktasi 2 sampai dengan 11 hari menunjukkan bobot testis dan kadar testosteron lebih rendah dibandingkan dengan kelompok yang tidak mendapatkan perlakuan apapun pada anak jantan usia 42 hari.
       
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      http://repository.ipb.ac.id/handle/123456789/57627
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      • UT - Anatomy, Phisiology and Pharmacology [1047]

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