Pengaruh Pemberian Ekstrak Sambiloto, Adas, dan Sirih Merah pada Ayam Broiler terhadap Infeksi Virus Avian Influenza: Histopatologi Hati dan Ginjal
The Effect of Sambiloto, Adas and Sirih Merah Extract on Avian Influenza Virus Infection in Broiler: Histopathology of Liver and Kidney.
dc.contributor.advisor | Setiyono,Agus | |
dc.contributor.author | Rahayu, Larasati Puji | |
dc.date.accessioned | 2012-01-18T07:38:15Z | |
dc.date.available | 2012-01-18T07:38:15Z | |
dc.date.issued | 2011 | |
dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/52994 | |
dc.description.abstract | The objective of this research was to study the effect of extract formulation of sambiloto (Andrographis paniculata), adas (Foeniculum vulgare), and sirih merah (Piper crocatum) to inhibit H5N1 avian influenza virus infection in broiler. Active compounds from each herb were andrographolide, anethole, and piperine respectively. Broiler was divided into eight groups, two as negative (no herbal, unvaccinated) and positive (no herbal, vaccinated) control and the other six groups were treated with herbal formula concentration given 5%, 7.5%, and 10% respectively. The six treated groups were split into three vaccinated and the remaining unvaccinated groups. After infected with H5N1 avian influenza virus, sample from each groups were necropsied and liver and kidney were taken to be evaluated histopathologically. Result of this study indicated that the group treated with 7.5% herb and vaccinated showing the mildest histopathological changes in both organs. | en |
dc.description.abstract | Penelitian ini bertujuan mengkaji pengaruh pemberian formula ekstrak sambiloto (Andrographis paniculata), adas (Foeniculum vulgare), dan sirih merah (Piper crocatum) dalam menghambat infeksi virus avian influenza H5N1 pada ayam broiler. Komponen aktif yang terkandung dalam masing-masing tanaman obat yakni andrografolid (sambiloto), anetol (adas), dan piperin (sirih merah). Ayam broiler dibagi menjadi delapan kelompok; dua kelompok masing-masing sebagai kontrol negatif (tanpa ekstrak, tanpa vaksinasi) dan kontrol positif (tanpa ekstrak, divaksin); enam kelompok diberi formula ekstrak dengan konsentrasi 5%, 7,5%, dan 10%. Keenam kelompok yang diberi formula ekstrak terdiri atas tiga kelompok divaksinasi, dan tiga kelompok tidak mendapat vaksinasi. Setelah diinfeksi dengan virus avian influenza H5N1, diambil satu sampel dari masingmasing kelompok untuk dinekropsi. Organ hati dan ginjal dari masing-masing sampel dibuat preparat histopatologi lalu diamati dan dievaluasi secara mikroskopis. Hasil penelitian ini mengindikasikan bahwa kelompok perlakuan yang diberi 7,5% formula ekstrak menunjukkan lesio histopatologi yang paling ringan dibandingkan dengan kelompok perlakuan lainnya. | |
dc.subject | broiler | en |
dc.subject | avian influenza | en |
dc.subject | herbal | en |
dc.subject | liver | en |
dc.subject | kidney | en |
dc.subject | Bogor Agricultural University (IPB) | en |
dc.title | Pengaruh Pemberian Ekstrak Sambiloto, Adas, dan Sirih Merah pada Ayam Broiler terhadap Infeksi Virus Avian Influenza: Histopatologi Hati dan Ginjal | en |
dc.title | The Effect of Sambiloto, Adas and Sirih Merah Extract on Avian Influenza Virus Infection in Broiler: Histopathology of Liver and Kidney. |