Sifat Hipoglisemik Pakan Tinggi Protein Kedelai pada Model Diabetik Induksi Alloxan
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Hypoglycemic properties of soybean protein were evdueted in dloxanjnduced diabetic rats. Twenly eight mslure mde Spregue Dawley (SD) rats (250300gJ were used and dMded into four p p s of seven d s . They wen: 1) Placebo Standevd (PS); 2) AUoxan injecth Standerd (AS); 3) A l l m injectiomoybecn protein 250% (APK 250) dm 4) Alloxm l~ection-soybecnp rodein #I%! (APK 100). One p u pw as injected with aquabidesf (Placebo) and three p p s were diabedk induced by dbxan Injection (80 mgKg of weight by inframusculav injection). PlaceMtandd (PS) and Alloxan injedion-Stand~(A~S ) pups were fed standerd diet whereas APK 250 and APK 100 were fed soybean protein diet fbr 42 days. Concentration of serum glucose was determined b e h injection (0 day.) and 1,7, 14,21,28,35 and 42, days Mer injection. The result showed thal alloxan injection increased the leva of sewn @me. Bioassay experiment demonstrated that diet on high concentration of soybean protein (25096) decreased the level of seturn $ucose from 351,44 mddl to 230,62 mgy'dl(34,37'??) while soy protein 100% decreaped the level of serum glucose frwn 404,513 mg'dl to 175,08 mgldl(56,72??). On the ofher h d , stand& diet were &led to decmsed the level of senrm glucose.