| dc.contributor.advisor | Estuningsih, Sri | |
| dc.contributor.advisor | Maylina, Leni | |
| dc.contributor.author | XUAN, LIEW | |
| dc.date.accessioned | 2025-07-07T08:54:14Z | |
| dc.date.available | 2025-07-07T08:54:14Z | |
| dc.date.issued | 2025 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/164066 | |
| dc.description.abstract | Feline Coronavirus (FCoV) is prevalent among domestic cats, particularly in multi-cat and outdoor-access environments, and can mutate into the fatal disease Feline Infectious Peritonitis (FIP). This study examined 45 FCoV-positive cats from a clinic in Selangor, Malaysia, using clinical evaluation, hematology, biochemistry, and Immunoassay titer testing. Infections were most common in cats aged 1 – 6 years. High antibody titers (= S5) linked with neurological, systemic, and gastrointestinal signs typical of FIP. Hematological findings included neutrophilia (60.71%), monocytosis (60.71%), and anemia (32.14%). Biochemical abnormalities include hyperbilirubinemia (100%), hypoalbuminemia (85.71%), hyperglobulinemia (89.29%), and low A/G ratios (100%) were consistent with FIP pathology. These results support the diagnostic value of combining clinical and laboratory data, while underscoring the need for improved FIP surveillance and early detection. | |
| dc.description.sponsorship | Coronavirus Kucing (FCoV) banyak ditemukan pada kucing domestik, terutama di lingkungan dengan banyak kucing yang memiliki akses ke luar rumah, serta dapat bermutasi menjadi penyakit mematikan Peritonitis Infeksius Felin (FIP). Studi ini mengevaluasi 45 kucing positif FCoV dari sebuah klinik di Selangor, Malaysia, melalui pemeriksaan klinis, hematologi, biokimia, dan uji titer imunisasi. Infeksi paling sering ditemukan pada kucing berusia 1–6 tahun. Titer antibodi tinggi (=S5) berkorelasi dengan gejala neurologis, sistemik, dan gastrointestinal yang khas pada FIP. Temuan hematologis meliputi neutrofilia (60,71%), monositosis (60,71%), dan anemia (32,14%). Kelainan biokimia seperti hiperbilirubinemia (100%), hipoalbuminemia (85,71%), hiperglobulinemia (89,29%), dan rasio albumin/globulin (A/G) rendah (100%) sesuai dengan patofisiologi FIP. Hasil ini mendukung nilai diagnostik dari kombinasi data klinis dan laboratorium, serta menyoroti pentingnya peningkatan pengawasan FIP dan deteksi dini. | |
| dc.language.iso | id | |
| dc.publisher | IPB University | id |
| dc.title | A Comprehensive Study of Clinical, Hematological, Biochemical, and Serological Profiles in Cats Infected with Feline Coronavirus (FCoV). | id |
| dc.title.alternative | Studi Komprehensif Profil Klinik, Hematologi, Biokimia, dan Serologi pada Kucing yang Terinfeksi Feline Coronavirus (FCoV). | |
| dc.type | Skripsi | |
| dc.subject.keyword | Feline infectious peritonitis (FIP) | id |
| dc.subject.keyword | Peritonitis Infeksius Felin (FIP) | id |
| dc.subject.keyword | hiperglobulinemia | id |
| dc.subject.keyword | Coronavirus Kucing (FCoV) | id |
| dc.subject.keyword | Biokimia | id |
| dc.subject.keyword | Immunoassay | id |
| dc.subject.keyword | hyperglobulinemia | id |
| dc.subject.keyword | uji titer imunisasi | id |
| dc.subject.keyword | Feline coronavirus (FCoV) | id |
| dc.subject.keyword | Biochemical | id |
| dc.subject.keyword | albumin/globulin (A/G) ratios | id |
| dc.subject.keyword | rasio albumin/globulin (A/G) | id |
