dc.contributor.advisor | Darusman, Huda Shalahudin | |
dc.contributor.advisor | Tumbelaka, Ligaya I.T.A. | |
dc.contributor.author | Alawi, Ahmad Addin Ghaffar | |
dc.date.accessioned | 2024-07-16T12:48:22Z | |
dc.date.available | 2024-07-16T12:48:22Z | |
dc.date.issued | 2024 | |
dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/153881 | |
dc.description.abstract | Protein amiloid beta 42 (Aß42) merupakan penanda biologis (biomarker) penyakit Alzheimer yang dapat dideteksi menggunakan kit ELISA. Penelitian ini bertujuan untuk mengetahui performa kit ELISA Aß42 inhouse di level serum dibandingkan dengan kit komersial. Penelitian ini dimaksudkan bermanfaat dalam mendeteksi dini penyakit Alzheimer dan pengembangan penelitian menggunakan kit ELISA inhouse IPB-PSSP. Penelitian ini menggunakan 18 sampel serum manusia yang dibagi menjadi 3 kelompok usia: kelompok 1 (20 – 30 tahun), kelompok 2 (30 – 40 tahun), dan kelompok 3 (> 40 tahun). Nilai OD antar kelompok dan antar kit dibandingkan rata-rata serta standar deviasinya. Hasil pengujian kit ELISA Aß42 inhouse memiliki performa yang mendekati kit ELISA komersial. | |
dc.description.abstract | Amyloid beta 42 (Aß42) protein is a biological marker (biomarker) of Alzheimer's disease that can be detected using an ELISA kit. This study aims to determine the performance of the in-house Aß42 ELISA kit at the serum level compared to the commercial kit. This research is intended to be beneficial for the early detection of Alzheimer's disease and for the development of research using the IPB-PSSP in-house ELISA kit. This study used 18 human serum samples divided into 3 age groups: group 1 (20-30 years), group 2 (30-40 years), and group 3 (> 40 years). The OD values between groups and between kits were compared using the average and standard deviation. The results of testing the in-house Aß42 ELISA kit show performance that is close to the commercial ELISA kit. | |
dc.description.sponsorship | | |
dc.language.iso | id | |
dc.publisher | IPB University | id |
dc.title | Deteksi Amiloid Beta 42 sebagai Marka Penyakit Alzheimer dengan Kit ELISA Inhouse IPB | id |
dc.title.alternative | Detection of Beta-Amyloid 42 as a Marker of Alzheimer's Disease Using the IPB In-house ELISA Kit | |
dc.type | Skripsi | |
dc.subject.keyword | alzheimer | id |
dc.subject.keyword | ELISA | id |