| dc.description.abstract | Bombay onion is a commonly consumed vegetable with known medicinal
properties, is hypothesized to possess anti-diarrheal effects due to its rich
phytochemical composition including flavonoids, phenolic compounds, and sulfur-
containing compounds, has demonstrated various biological activities, such as anti-
inflammatory, antioxidant, and antimicrobial effects. In this study, Bombay onion
infusion was evaluated for its anti-diarrheal efficacy using intestinal protection
method and determine the most effective concentration. Phytochemical analysis
was carried out to identify the bioactive compounds present in plant materials.
This research used 25 mice which divided into five groups: negative control,
positive control and three treatment groups was given orally with concentration of
25%, 50% and 100%. The parameters used in the intestinal protection method
were frequency of defecation, consistency of feces and duration of diarrhea. This
study concluded that Bombay onion infusion contain secondary metabolites such
as alkaloid, saponin and tannin and infusion with concentration of 25% showed the
most effective result. | |
