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      Studi Kasus Kuda Penghasil Antisera: Pemeriksaan Makroskopis dan Pengujian Biokimiawi Urine

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      Date
      2024
      Author
      Pasa, Desvira Rohma Al
      Tarigan, Ronald
      Setiyono, Agus
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      Abstract
      Studi kasus ini bertujuan mendeskripsikan gambaran makroskopis urine kuda penghasil antisera serta mengetahui komposisi biokimiawi urine menggunakan dipstick. Sampel urine diperoleh melalui metode free catch dari 6 ekor kuda produksi anti bisa ular serum, 2 ekor kuda produksi anti tetanus serum, 1 ekor kuda produksi anti difteri serum, dan 3 ekor kuda kontrol. Pemeriksaan makroskopis dilakukan dengan melihat warna dan bau urine. Pemeriksaan biokimiawi urine dilakukan terhadap 10 parameter yaitu leukosit, nitrit, urobilinogen, protein, darah (eritrosit), pH, berat jenis, keton, bilirubin, dan glukosa. Hasil pengujian menunjukkan 1 ekor kuda yang memproduksi anti bisa ular serum memiliki warna urine kecoklatan dan bau amonia yang menyengat. Parameter biokimiawi urine yang berubah adalah leukosit, protein, darah, bilirubin, dan glukosa. Imunogen bisa ular, tetanus, dan difteri yang disuntikkan pada kuda penghasil antisera menyebabkan perubahan komposisi biokimiawi urine. Penyuntikan dengan imunogen bisa ular mengakibatkan perubahan parameter yang paling banyak dibandingkan dengan imunogen toksoid tetanus dan toksoid difteri.
       
      This case study was aimed to describe the macroscopic appearance of antisera-producing horse urine and determine the biochemical composition of urine using a dipstick. Urine samples were obtained using the free catch method from 6 horses producing anti-snake venom serum, 2 horses producing anti-tetanus serum, 1 horse producing anti-diphtheria serum, and 3 control horses. Macroscopic examination was carried out by observing the color and odor of urine. Urine biochemical examination was carried out on 10 parameters, namely leukocytes, nitrites, urobilinogen, protein, blood (erythrocyte), pH, specific gravity, ketones, bilirubin, and glucose. Test results showed that 1 horse that produced anti-snake venom serum had brownish urine and a strong smell of ammonia. The immunogens of snake venom, tetanus, and diphtheria injected into antisera-producing horses cause changes in the biochemical composition of urine. The biochemical parameters of urine that change are leukocytes, protein, blood, bilirubin and glucose. Injection with snake venom immunogen resulted in the most changes in parameters compared to tetanus toxoid immunogen and diphtheria toxoid immunogen.
       
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      http://repository.ipb.ac.id/handle/123456789/153336
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      • UT - Veterinary Clinic Reproduction and Pathology [2186]

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      Copyright © 2020 Library of IPB University
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      Indonesia DSpace Group 
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      Universitas Jember Digital Repository