| dc.description.abstract | The benefit of specific immunoglobulin Y (Ig Y) as an active ingredient in
personal care products such as sunscreen has not been properly studied. Our study
aims to evaluate the reliability of specific IgY against influenza and the COVID-19
virus in a sample sunscreen product. Specific IgY influenza and COVID-19 viruses
were inserted in the sample sunscreen at two concentrations of 0.1% and 0.25%.
Three treatments were observed: control (C) sunscreen without IgY, treatment 1
(T1) sunscreen with 0.1% IgY, and treatment 2 (T2) sunscreen with 0.25% IgY.
Organoleptic observations were carried out to monitor changes in aroma, color, and
texture, and sunscreen sampling was done every week for 6 weeks. The durability
of IgY was evaluated using an enzyme-linked immunosorbent assay (ELISA) and
a neutralization assay. Organoleptic observation from weeks 1 to 6 showed
consistency in its aroma, color, and texture. Enzyme-linked immunosorbent assay
and neutralization assay (NA) results of the T1 and T2 groups showed negative
results except for sample T1 at week 5, which showed a positive result in the
Influenza A ELISA. Based on the results, it seems that IgY concentrations of 0.1%
or 0.25% were not optimal. However, this negative result might be due to low
concentration of the IgY and the presence of beeswax, which inhibits IgY and
causes it to dissolve in distilled water, thus preventing it from being detected in the
assay. | id |
