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      Efektivitas Minyak Kemiri (Aleurites moluccana L.) sebagai Penumbuh Rambut pada Tikus (Rattus norvegicus).

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      Date
      2023
      Author
      Miftahurahma, Nabila Martha Ludi
      Manalu, Wasmen
      Ilyas, Abdul Zahid
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      Abstract
      Rambut rontok merupakan masalah yang banyak dijumpai dan mengakibatkan kebotakan. Kebotakan dapat dicegah dengan produk sintetis maupun herbal, namun produk sintetis dapat menimbulkan efek samping. Minyak kemiri mampu menjadi alternatif pengobatan karena terbuat dari bahan alam dan aman digunakan. Penelitian ini bertujuan menguji efektivitas minyak kemiri sebagai penumbuh rambut. Kelompok perlakuan terdiri atas kelompok kontrol tanpa pengolesan (A), kelompok dengan pengolesan sekali sehari (B), kelompok dengan pengolesan dua kali sehari (C), dan kelompok dengan pengolesan tiga kali sehari (D). Panjang rambut diukur dan uji iritasi dilakukan pada hari ke-6, 9, 12, dan 15 dengan perlakuan diberikan setiap hari secara topikal pada punggung tikus yang telah dicukur. Hasil penelitian menujukkan bahwa minyak kemiri memiliki efektivitas sebagai penumbuh rambut. Uji efektivitas minyak kemiri sebagai penumbuh rambut menunjukkan pertumbuhan rambut yang lebih cepat secara statistik dibandingkan kontrol pada frekuensi pengolesan tiga kali sehari dan tidak berbeda nyata dibandingkan dengan pengolesan satu kali dan dua kali sehari. Uji iritasi yang dilakukan tidak menunjukkan adanya iritasi pada punggung tikus.
       
      Hair loss is a common problem and it can cause baldness. Baldness may be prevented with synthetic or herbal product, however synthetic products may have side effects. Candlenut oil can be used as an alternative treatment because it is made from natural ingredients and also safe to use. This study aims to test the effectiveness of pure candlenut oil as hair growth promoters. The treatment groups consisted of control rats without smearing of candlenut oil (A), rats receiving smearing of candlenut oil once a day (B), rats receiving smearing of candlenut oil twice a day (C), and rats receiving smearing of candlenut oil three times a day (D). Hair length was measured and irritation tests were carried out on day 6th, 9th, 12th, and 15th with the topical treatment daily on the shaved areas at the back of the rats. The results of the study show that pure candlenut oil has effectiveness as hair growth promoter. The fastest hair growth was found in rats receiving smearing of candlenut oil three times a day. There was no significant difference in hair growth in rats receiving smearing of candlenut oil once and twice a day compare to control. The irritation test did not show any sign of irritation on the rat's back.
       
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      http://repository.ipb.ac.id/handle/123456789/121962
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      • UT - Anatomy, Phisiology and Pharmacology [1047]

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