dc.contributor.advisor | Arif, Ridi | |
dc.contributor.advisor | Setiadi, Mohamad Agus | |
dc.contributor.author | H, Tasya Anum | |
dc.date.accessioned | 2023-07-13T04:33:39Z | |
dc.date.available | 2023-07-13T04:33:39Z | |
dc.date.issued | 2023-07-13 | |
dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/121731 | |
dc.description.abstract | Haemonchus contortus merupakan salah satu parasit ruminansia yang
patogen dan telah menimbulkan resistensi terhadap pengobatan antelmintik
sintetik. Penelitian ini menguji efektivitas antelmintik daun kemangi skala mikron
secara in vitro terhadap telur, larva infektif (L3), dan cacing dewasa H. contortus. Efektivitas tiga macam konsentrasi mikroherbal (10, 5, dan 1%) diuji melalui egg
hatch assay, larval motility inhibition test, and adult worm motility inhibition
assay. Kelompok kontrol negatif menggunakan PBS 10% sementara kontrol
positif menggunakan Albendazole 10 mg/ml. Hasil penelitian menunjukkan
bahwa perlakuan mikroherbal konsentrasi tertinggi (10%) memiliki efek yang
tidak berbeda nyata dengan Albendazole (p>0,05), baik terhadap telur, L3,
maupun cacing dewasa. Penghambatan motilitas seluruh cacing dewasa terjadi
pada 1-4 jam pertama paparan mikroherbal 10%. Mikroherbal daun kemangi
efektif dijadikan antelmintik terhadap berbagai stadium H. contortus. | id |
dc.description.abstract | Haemonchus contortus is one of the prevalent and pathogenic ruminant
parasites that has grown resistance to common anthelmintic treatment. This study
evaluated the anthelmintic effectiveness of Ocimum africanum leaf on a micron
scale against H. contortus eggs, infective stage larvae (L3s), and adult worm. The
efficacy of three microherbal concentrations (10, 5, and 1 %) were tested through
egg hatch assay, larval motility inhibition test, and adult worm motility inhibition
assay. The negative control group used 10% PBS while the positive control used
Albendazole 10 mg/ml. The results of this study indicated that the highest
concentration (10%) of microherbal treatment had an effect that was not
significantly different from Albendazole (p>0.05), both on eggs, L3, and adult
worms. Adult worms completely immobilized within the first 1-4 hours of
exposure to 10% microherbal. Basil leaves in the form of microherbals were
effective as an anthelmintic against various stages of H. contortus. | id |
dc.language.iso | id | id |
dc.publisher | IPB University | id |
dc.title | Efektivitas Mikorherbal Daun Kemangi sebagai Antelmintik terhadap Haemonchus contortus pada Pengujian In Vitro | id |
dc.type | Undergraduate Thesis | id |
dc.subject.keyword | anthelmintic | id |
dc.subject.keyword | basil leaf (Ocimum africanum) | id |
dc.subject.keyword | Haemonchus contortus | id |
dc.subject.keyword | microherbal | id |