Show simple item record

dc.contributor.advisorMustika, Aulia Andi
dc.contributor.advisorNugraha, Arifin Budiman
dc.contributor.authorSavira, Annisa Putri Rahma
dc.date.accessioned2023-07-11T13:45:04Z
dc.date.available2023-07-11T13:45:04Z
dc.date.issued2023
dc.identifier.urihttp://repository.ipb.ac.id/handle/123456789/121445
dc.description.abstractGum arab dan daun keji beling merupakan dua herbal yang telah banyak dimanfaatkan dalam pengobatan tradisional dan diketahui memiliki kandungan fitonutrien yang berpotensi sebagai antidiare. Penelitian ini bertujuan mengetahui efektivitas kombinasi infusa gum arab dan daun keji beling (Strobilanthes crispa Bl.) sebagai antidiare, menentukan konsentrasi yang paling efektif dalam memberikan efek antidiare, serta menguji aktivitas antidiarenya pada mencit. Pengujian efektivitas antidiare dilakukan dengan metode proteksi intestinal dan transit intestinal untuk mengetahui kemampuan sediaan dalam menghambat frekuensi defekasi, memperbaiki konsistensi feses, dan mengurangi motilitas usus. Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa kombinasi infusa gum arab dan infusa daun keji beling dengan konsentrasi 50% efektif dalam menghambat diare pada mencit. Namun, konsentrasi 100%, 25%, dan 12,5% tidak menunjukkan adanya efek antidiare. Aktivitas antidiare kombinasi infusa gum arab dan daun keji beling ditunjukan oleh penurunan frekuensi defekasi, perbaikan konsistensi feses, dan penghambatan motilitas usus.id
dc.description.abstractArabic gum and keji beling leaves are two herbs widely used in traditional medicine and are known to contain phytonutrients that have the potential as an antidiarrheal. The purpose of this study was to assess the effectiveness of a combination of gum arabic and keji beling (Strobilanthes crispa Bl.) leaf infusion as an antidiarrheal, to find the most effective concentration for giving antidiarrheal effects and to test its antidiarrheal activity on mice. The effectiveness of the antidiarrheal was evaluated using the intestinal protection and intestinal transit methods to determine the preparation's capacity to reduce defecation frequency, improve stool consistency, and reduce intestinal motility. Based on the results of this study, it was concluded that a mixture of 50% gum arabic infusion and keji beling leaf infusion could effectively prevent diarrhea in mice. However, 100%, 25%, and 12.5% concentrations had no such effect. The antidiarrheal activity of the combination of gum arabic and keji beling leaf infusion was indicated by a decrease in the frequency of defecation, improvement in stool consistency, and inhibition of intestinal motility.id
dc.language.isoidid
dc.publisherIPB Universityid
dc.titleEfektivitas Kombinasi Infusa Gum Arab dan Daun Keji Beling sebagai Antidiare pada Mencitid
dc.title.alternativeEffectiveness of Combination Arabic Gum and Keji Beling Leaf Infusion as Antidiarrheal in Miceid
dc.typeUndergraduate Thesisid
dc.subject.keywordantidiarrhealid
dc.subject.keywordarabic gumid
dc.subject.keywordkeji belingid


Files in this item

Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record