| dc.contributor.advisor | Sari, Rita Kartika | |
| dc.contributor.advisor | Carolina, Anne | |
| dc.contributor.author | Setiadi, Afriza | |
| dc.date.accessioned | 2022-08-12T08:23:34Z | |
| dc.date.available | 2022-08-12T08:23:34Z | |
| dc.date.issued | 2022-08-07 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/113532 | |
| dc.description.abstract | Penuaan kulit dapat dicegah dengan menggunakan krim anti-aging, tetapi
umumnya berbahan aktif sintetik yang berbahaya dan impor. Nanofitosom dan
nanoemulsi kombinasi ekstrak kayu merbau dan daun pegagan (KE) menjadi
subsitusinya. Penelitian ini bertujuan menentukan stabilitas sifat fisikokimia empat
belas formula krim berbahan aktif KE1:2 (F1:1,2%; F2:2,4%), KE2:1 (F3:4%;
F4:8%), nanoemulsi KE1:2 (F5:4%; F6:8%), nanoemulsi KE2:1 (F7:4%; F8:8%),
nanofitosom KE1:2 (F9:4%; F10:8%), nanofitosom KE2:1 (F11:4%; F12:8%),
kontrol negatif (KN), dan kontrol positif (KP) yang disimpan pada suhu ruang
selama 21 hari. Hasil penelitian menunjukkan homogenitas, warna, dan aroma
semua formula krim stabil. Kecuali F2 dan F12, kedua belas formula krim
memenuhi standar SNI 16-4399- 1996 untuk nilai pH, viskositas, dan daya sebar.
Formula krim KP, F3, F4, F5, F6, F7, dan F8 termasuk krim terbaik untuk
diaplikasikan pada wajah karena memiliki pH sekitar 4,5-6,5. Penyimpanan selama
21 hari mempengaruhi nilai pH, viskositas, dan daya sebar formula krim tersebut,
tetapi masih memenuhi standar SNI 16-4399- 1996. | id |
| dc.description.abstract | Skin aging can be prevented by using anti-aging creams, but generally using
synthetic active ingredients that are dangerous and imported. The combination of
merbau woods extract and pegagan leaves (KE) became the substitute. To improve
its bioavailability, KE was made into nanophytosome and nanoemulsion. This study
aim to determine the stability of the physicochemical properties of fourteen cream
formulas with active ingredients KE1:2 (F1:1,2%; F2:2,4%), KE2:1 (F3:4%;
F4:8%), KE1 nanoemulsion: 2 (F5:4%; F6:8%), KE2:1 nanoemulsion (F7:4%;
F8:8%), KE1:2 nanophytosome (F9:4%; F10:8%), KE2:1 nanophytosome
(F11:4%; F12:8%), negative control (KN), and positive control (KP). The creams
were stored at room temperature for 21 days. The results showed that all cream
formulas' homogeneity, color, and aroma were stable. Except for F2 and F12, the
twelve cream formulas met the standards of SNI 16-4399-1996 for the value of pH,
viscosity, and spreadability. KP, F3, F4, F5, F6, F7, and F8 cream formulas are
among the best creams to be applied to the face because they have a pH value of
around 4.5-6.5. The storage for 21 days affected the pH value, viscosity, and
spreadability, but they still met the standard of SNI 16-4399-1996. | id |
| dc.language.iso | id | id |
| dc.publisher | IPB University | id |
| dc.title | Stabilitas Fisikokimia Formula Krim Anti-aging Berbahan Aktif Nanoemulsi dan Nanofitosom Ekstrak Kayu Merbau dan Daun Pegagan | id |
| dc.title.alternative | Physicochemical Stability of Anti-aging Cream Formulas with Active Ingredients of Nanoemulsion and Nanophytosome of Merbau Wood Extracts and Pegagan Leaf Extracts Combination | id |
| dc.type | Undergraduate Thesis | id |
| dc.subject.keyword | spreadability | id |
| dc.subject.keyword | homogeneity | id |
| dc.subject.keyword | organoleptic | id |
| dc.subject.keyword | pH | id |
| dc.subject.keyword | viscosity | id |
