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      Profil Ureum Nitrogen dan Kreatinin Darah pada Anjing yang Diberi Anti Caplak Berbahan Aktif Sarolaner di Direktorat Polisi Satwa Baharkam Polri Kelapa Dua Depok

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      Date
      2021
      Author
      Hidayah, Yola Salsabila
      Soviana, Susi
      Dewi, Tri Isyani Tungga
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      Abstract
      Blood Urea Nitrogen (BUN) dan kreatinin darah merupakan parameter yang dapat menunjukkan adanya gangguan fungsi ginjal. Penelitian ini bertujuan menganalisis profil BUN dan kreatinin darah anjing yang diberikan anti caplak berbahan aktif sarolaner. Sarolaner dalam dosis tunggal diberikan secara per oral kepada 5 ekor anjing yang terinfestasi caplak, kemudian dilakukan pengambilan darah melalui vena cephalica antebrachii. Pengukuran kadar BUN dan kreatinin darah anjing dilakukan pada sehari sebelum perlakuan (H-0), seminggu (H+7), dan sebulan setelah perlakuan (H+30). Alat yang digunakan untuk mengukur kadar BUN dan kreatinin darah adalah Arkray Spotchem TM EZ 4430. Data profil BUN dan kreatinin darah kelima anjing berdasarkan waktu pengamatan dianalisis menggunakan uji one way ANOVA. Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan nyata pada kadar BUN dan kreatinin darah anjing di berbagai waktu pengamatan (P>0.05). Rata-rata kadar BUN dan kreatinin darah anjing masih berada dalam rentang normal. Hal ini dapat mengindikasikan bahwa pemberian anti caplak berbahan aktif sarolaner dosis tunggal tidak mempengaruhi fungsi ginjal.
       
      Blood Urea Nitrogen (BUN) and blood creatinine are parameters that can indicate impaired kidney function. This study aims to analyze the profile of BUN and blood creatinine in dogs that are treated with a single dose of sarolaner-active ingredients. Sarolaner in a single dose was given orally to 5 dogs that were infested with ticks, then blood was drawn through the cephalic antebrachii vein. Measurements of BUN and dog blood creatinine were carried out one day before treatment (H-0), a week (H+7), and a month after treatment (H+30). The instrument used to measure BUN and blood creatinine levels was Arkray Spotchem TM EZ 4430. Data on BUN and blood creatinine profiles of the five dogs based on time of observation were analyzed using the one way ANOVA test. The results showed that there was no significant difference in the levels of BUN and blood creatinine in dogs at various observation times (P>0.05). The average BUN and blood creatinine levels of dogs were still in the normal range. This may indicate that the administration of a single dose of Sarolaner does not affect kidney function.
       
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      http://repository.ipb.ac.id/handle/123456789/108266
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      • UT - Animal Disease and Veterinary Health [1240]

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      Indonesia DSpace Group 
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