| dc.date.accessioned | 2019-12-26T06:36:23Z | |
| dc.date.available | 2019-12-26T06:36:23Z | |
| dc.date.issued | 2017-10-15 | |
| dc.identifier.uri | http://repository.ipb.ac.id/handle/123456789/100557 | |
| dc.description | The spleen is the largest lymphoid organ [1]. As a secondary lymphoid organ, in addition to its immune function, the spleen also has functions as blood filtration, storage, and hematopoiesis [2]. The spleen has different morphologies between species that support different physiological functions, one of which is the difference in the structure of the connective tissue architecture [3]. Bats are the reservoir of various zoonotic diseases. Bats are thought to have unique immune systems compared to other mammals but the characteristics of its immune organs such as the spleen have never been studied before [4]. This study was conducted to examine the characteristics of connective tissue of the Common Rousette (Rousettus amplexicaudatus) spleen. This study was carried out on one spleen obtained from wild captured Common Rousette. Spleen was fixed in paraformaldehyde 4% solution and then prepared for paraffin section. The spleen was cut at 5 μm and then stained with hematoxylin and eosin, Masson's trichrome Goldner modification, and Verhoeff Van Gieson methods. The Common Rousette spleen was composed of a thin capsule surrounding spleen parenchyma. The capsule was composed predominantly of connective tissue which is mainly collagen fiber with few scattered elastin fiber and smooth muscle. The capsule extended into the parenchyma become trabecula. Trabecula was latter divided into primary and secondary trabecula. The primary trabecula originated from the capsule and had a similar structure with the capsule. The secondary trabecula was composed mainly of smooth muscle cells with collagen fibers among them and also a few elastin fibers. Trabecula divided red pulp into small compartments called cord which is composed of collagenous network. In general, the characteristics of connective tissue in the spleen of Common Rousette was similar with human and mice spleen architecture [5][6]. Therefore, the Common Rousette spleen may has the same physiological function with human and mice. | id |
| dc.description.abstract | The spleen is the largest lymphoid organ. As a secondary lymphoid organ, in addition to its immune function, the spleen also has functions as blood filtration, storage, and hematopoiesis. The spleen has different morphologies between species that support different physiological functions, one of which is the difference in the structure of the capsule and trabeculae. Capsule and trabeculae of the spleen generally consist of connective tissue and smooth muscle. The thickness of smooth muscle composed together with connective tissue in the capsule and trabecula determines the function of the spleen that is divided spleen into three storage, defense, and intermediate. Bats are the reservoir of various zoonotic diseases. Bats are thought to have unique immune systems compared to other mammals but the characteristics of its immune organs such as the spleen have never been studied before. This study was conducted to examine the characteristics of capsulae and trabecula of the Common Rousette (Rousettus amplexicaudatus). | id |
| dc.description.sponsorship | The Grant of Pendidikan Magister Menuju Doktor untuk Sarjana Unggul (PMDSU) Ministry of Research, Technology, and Higher Education, Indonesia | id |
| dc.language.iso | en_US | id |
| dc.publisher | IPB (Bogor Agricultural University) | id |
| dc.title | Light Microscope Study of ConnectiveTissue in The Spleen of Common Rousette Bat (Rousettus amplexicaudatus) | id |
| dc.type | Other | id |
