Kapang Endofit dari Mangrove Rhizophora mucronata dan Potensinya Sebagai Antidiare

Abstract

Mangrove plants are known as source of traditional medicines. Endophytic fungi have important economic potential for antibacterial, enzyme and secondary metabolites that are useful especially in pharmaceutical industry. The purpose of this research was to determine the antibacterial activity of the endophytic fungi extract from mangrove Rhizophora mucronata against bacteria that cause diarrhea. This research included isolation, characterization, cultivation, extraction, and antibacterial activities test. The study yielded 5 types of endophytic fungi with different morphology. Endophytic fungus A was the selected isolate based on antagonism test. The growth patterns showed the stationary phase of isolate A was on the 15th day. The result of antibacterial test of culture broth extract showed considerable inhibition on Pseudomonas aeruginosa 18.5 mm ± 3.32. Extract of mycelium showed inhibition on Staphylococcus aureus 2 mm. The culture broth extract was more effective as antidiarrhoeal in comparison with the mycelium.