Short chain fatty acid (SCFA) profile produced by Clostridium butyricum grown on medium containing type 3 resistant starch (RS3) of sweet potato

Abstract

Gastrointestines is an important part of body metabolism which affects human health. One of the deseases which attack gastrointestines is colorectal cancer (CRC) which can be prevented by proper lifestyle and consumption of healthy functional food. SCFA are the main products of anaerobic microbial fermentation in the large intestine and affect colonic health by providing energy to the epithelial cells. The organic acids produced in the colon are acetic acid, propionic acid, and butyric acid. Interest in butyrate role as a possible protective agent has arisen from its anti-proliferative effects on cells in vitro including colon tumour cell lines. Resistant starch (RS), is retrogradaded starch that escapes digestion in the small intestine and can be fermented in colon by anaerobic bacteria producing SCFA which contributes to the gastrointestinal health, and thus can be classified as funtional food. The crystalline non-granular starch (RS3) can be obtained from many starchy sources, such as rice, corn, maize, wheat, sago, banana, potato, and sweet potato. In this study, jago sweet potato used contain 31% starch content. Jago sweet potato is usually consumed indirectly as the taste is not preferable.