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Title: | Efek suplementasi ekstrak protein kecambah kedelai terhadap Kadar il-1beta penderita diabetes tipe-2 |
Other Titles: | The Effect of Soy Germ Protein Extract Supplementation on the Level of IL-1 Beta of Type-2 Diabetic Woman Jurnal Teknologi dan Industri Pangan Vol 21 No 1 tahun 2010 |
Authors: | Winarsi, Hery Purwanto, Agus |
Issue Date: | 2010 |
Publisher: | IPB (Bogor Agricultural University) |
Abstract: | The research was conducted to determine the effect of soy germ protein extract supplementation on the IL-1beta level of type-2 diabetic women. Research subjects were 32 type-2 diabetic women, outpatients of Diabetic Clinics of Margono Soekarjo General Hospital-Purwokerto. These women had blood glucose level above normal, BMI > 23 kg/m2, over 40 years old, lived in Purwokerto, and signed the informed consent. Group A (n=8) was given milk containing soy germ protein extract plus Zinc, Group B (n=8) was given milk containing soy germ protein extract without Zinc, Group C (n=8) was given placebo, and Group D (n=8) was given glibenclamide for 8 weeks. Blood samples ware taken 3 times: 0, 4 and 8 weeks after intervention. The plasma IL-1beta level was analyzed using Elisa. After 8 weeks, the IL-1beta level decreased from 6.01 pg/mL to 2.63 pg/mL (p=0.022) in group A. However, the IL-1beta level in Group A was not different from the Group B (p=0.51). Soy germ protein extract decreased cytokine inflammatory production of type-2 dibetic. Soy germ protein extract with or without Zn had similar effects to glibenclamide in reducing the IL-1beta level (p=0.76). |
URI: | http://repository.ipb.ac.id/handle/123456789/45708 |
Appears in Collections: | Jurnal Teknologi dan Industri Pangan |
Files in This Item:
File | Description | Size | Format | |
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J.Teknologi & Industri Pangan, Vol 21, No 1 (2010) - efek suplementasi ekstrak.doc | Abstract | 25.5 kB | Microsoft Word | View/Open |
J.Teknologi & Industri Pangan, Vol 21, No 1 _2010_ - efek suplementasi ekstrak.pdf | journal | 54.78 kB | Adobe PDF | View/Open |
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