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Title: | Efek Antihiperglikemik Ekstrak Etanol Daun Mimba (Azadirachta Indica J) Pada Tikus Diabetes yang Diinduksi Aloksan dan Pengembangannya Menjadi Sediaan Tablet Menggunakan Metode Granulasi Basah (Antihyperglycaemic Effect Of Azadirachta Indica J Extract On Alloxsan – Induced Diabetic Rat And Tablet Formulation Used Wet Granulation) |
Other Titles: | Prosiding Seminar Hasil Penelitian IPB 2009 Buku 3 Bidang Kesehatan |
Authors: | Priosoeryanto, Bambang Pontjo Prasetyo, Bayu Febram Wientarsih, Ietje Madyastuti, Rini |
Keywords: | Azadirachta indica J, antihyperglycaemic, alloxan, ethanol extract |
Issue Date: | 2009 |
Publisher: | IPB (Bogor Agricultural University) |
Abstract: | This study was aimed to determine antihyperglycaemic effect of Azadirachta indica J extract on alloxan-induced diabetic rat, active compound indentification, and tablet formulation This study used 18 mice Spraque Dawley strains are divided into 6 groups. The results of this study indicate that extracts dose given orally 30, 60 and 90mg / kg body weight showed a decrease of blood glucose levels of diabetes mice alloxsan significant (P <0.05) by 7%, 8%, and 14.8% after giving repeatedly extracts on the tenth day compared with the sixth day. Indentification of flavonoid compound showed antocianidin which have flavylium (2-fenil-benzopyrylium) ion on the first fraction and the second fraction showed antocianidin : ion flavylium (2-fenil-benzopyrylium) , 7- hidroksi flavylium 4'-hidroksi flavylium, and 3,4,7'-trihidroksi flavylium Mimba extract could be made on tablet formulation used PVP K-30 on wet granulation. |
URI: | http://repository.ipb.ac.id/handle/123456789/45134 |
Appears in Collections: | Proceedings |
Files in This Item:
File | Description | Size | Format | |
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Efek Antihiperglikemik Ekstrak.pdf | Prosiding | 195.75 kB | Adobe PDF | View/Open |
Efek Antihiperglikemik Ekstrak_abstract.pdf | Abstract | 202.61 kB | Adobe PDF | View/Open |
Efek Antihiperglikemik Ekstrak.doc | Abstract | 28.5 kB | Microsoft Word | View/Open |
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