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http://repository.ipb.ac.id/handle/123456789/153219
Title: | Gambaran Leukosit Kelinci pada Kondisi Syok Hemoragik dengan Terapi Resusitasi Hipotensif dan Dexamethasone |
Other Titles: | Profile of Rabbit Leukocyte in Shock Hemorrhagiic Condition with Teraphy Resuscitation Hipotensif and Dexamethasone |
Authors: | Gunanti Esfandiari, Anita Aziziah, Nurul Madinah |
Issue Date: | 2024 |
Publisher: | IPB University |
Abstract: | Syok hemoragik merupakan penyebab utama dari morbiditas dan mortalitas
pada pasien bedah dan trauma. Penelitian ini bertujuan untuk mendeskripsikan
gambaran leukosit kelinci dalam kondisi syok hemoragik, serta mengidentifikasi
pengaruh terapi dan pemberian dexamethasone. Penelitian ini menerapkan induksi
syok dengan volume tetap, kemudian diberikan terapi menggunakan resusitasi
hipotensif dan dexamethasone. Data dalam penelitian ini menggunakan 6 ekor
kelinci normal yang dibagi menjadi dua kelompok, yaitu kelompok tanpa terapi dan
kelompok terapi resusitasi hipotensif dan dexamethasone. Hasil penelitian
menunjukkan bahwa pada kondisi syok hemoragi jumlah leukosit kelinci dan
diferensialnya mengalami penurunan. Kelompok tanpa terapi dan kelompok terapi
menunjukkan profil leukosit kelinci dan diferensialnya mengalami kenaikan
kembali. Hasil setelah pemberian terapi resusitasi hipotensif dan dexamethasone
secara statistik tidak signifikan sehingga tidak memengaruhi jumlah leukosit pada
kelinci yang mengalami syok hemoragi. Hemorrhagic shock is a major cause of morbidity and mortality in surgical and trauma patients. This study aims to describe the leukocyte picture of rabbits in hemorrhagic shock, and identify the effect of therapy and dexamethasone administration. This study applies shock induction with a fixed volume, then therapy is given using hypotensive resuscitation and dexamethasone. The data in this study used 6 normal rabbits which were divided into two groups, namely the group without therapy and the hypotensive resuscitation and dexamethasone therapy group. The results showed that in the condition of hemorrhagic shock, the number of rabbit leukocytes and their differential decreased. The group without therapy and group given therapy showed that the rabbit leukocytes profile and differentials had increased again. The hypotensive resuscitation therapy and dexamethasone therapy group were statistically insignificant so they did not affect the number of leukocytes in rabbits experiencing hemorrhagic shock. |
URI: | http://repository.ipb.ac.id/handle/123456789/153219 |
Appears in Collections: | UT - Veterinary Clinic Reproduction and Pathology |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Cover, Lembar Pernyataan, Abstrak, Lembar Pengesahan, Prakata dan Daftar Isi.pdf Restricted Access | Cover | 350.11 kB | Adobe PDF | View/Open |
B0401201014_Nurul Madinah Aziziah.pdf Restricted Access | Fulltext | 577.4 kB | Adobe PDF | View/Open |
Lampiran.pdf Restricted Access | Lampiran | 149.76 kB | Adobe PDF | View/Open |
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