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Title: | Histopatologi hati ayam yang diinfeksi Ascaridia galli dan diobati ekstrak etanol akar daruju [Acanthus ilicifolius Linn.] |
Authors: | Harlina, Eva Tiuria, Risa Kusumaningtyas, Pratiwi |
Issue Date: | 2009 |
Publisher: | IPB University |
Abstract: | The aim of this research is to examine the histopathological changes of chicken liver treated by 70% ethanol extract of Acanthi radix as the anthelmintic against Larva-3 A. galli. Eighteen chickens were divided into six groups, which were control group (without any treatment), negative control group (without medicinal treatment), positive control group treated by pyrantel pamoate 54.25 mg/kg BW, treated groups by 70% extract of Acanthi radix which doses were 124 mg/kg BW, 248 mg/kg BW and 496 mg/kg BW, per oral for 3 days. The result of liver histopathological evaluation showed hydropic degeneration and apoptosis of hepatocytes on every group observed. The hydropic degeneration was not significantly different (p>0.05) among the groups. This research also showed that apoptosis of groups treated by extract of Acanthi radix were significantly higher (p<0.05) than pyrantel pamoate group. The treatment of 70% ethanol extract of Acanthi radix tends to make apoptosis of hepatocytes but still in mild changes. Keywords: Acanthi radix, A. galli, extract, chicken liver, histopathology, toxicity. |
URI: | http://repository.ipb.ac.id/handle/123456789/139807 |
Appears in Collections: | UT - Veterinary Clinic Reproduction and Pathology |
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File | Size | Format | |
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B09pku.pdf Restricted Access | 10.02 MB | Adobe PDF | View/Open |
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