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Title: | Identifikasi Metabolit dan Pengelompokkan Sidaguri (Sida rhombifolia .L) dari Lokasi Tumbuh Berbeda Menggunakan LC-MS/MS |
Other Titles: | Identification of Metabolites and Grouping of Sidaguri (Sida rhombifolia L.) from Different Growing Locations Using LC-MS/MS |
Authors: | Ilmiawati, Auliya Rafi, Mohamad Alfarisi, Ilham |
Issue Date: | 2022 |
Publisher: | IPB University |
Abstract: | Tumbuhan obat telah banyak digunakan untuk berbagai macam tujuan, baik
untuk mencegah maupun mengobati penyakit. Salah satu spesies tanaman yang
digunakan sebagai ramuan obat tradisional di Indonesia ialah sidaguri (Sida
rhombifolia). Penelitian ini bertujuan mengidentifikasi kandungan senyawa ekstrak
metanol herba spesies tersebut dari lokasi tumbuh berbeda. Analisis ekstrak
metanol herba sidaguri diklasifikasikan berdasarkan lokasi tumbuh di Malang,
Solo, Sukabumi, Tawangmangu, dan Yogyakarta menggunakan kromatografi cair-
spektrometri massa dan dikelompokan menggunakan principal component
analysis. Sebanyak 17 senyawa berhasil teridentifikasi dalam ekstrak. Senyawa
tersebut termasuk dalam golongan fenolik, alkaloid, steroid, flavonoid,
monoterpena lakton, dan golongan asam amino dan asam lemak. Didapatkan pola
fragmentasi untuk 17 senyawa dengan cara fragmentasi spektrum massa
berdasarkan kelompok senyawa masing-masing. Senyawa yang terdapat pada
sampel terkelompok sesuai dengan lokasi tumbuhnya masing-masing dengan total
varians 66%. Medicinal plants have been widely used for various purposes, both to prevent and treat diseases. One of the plant species used as traditional medicinal ingredients in Indonesia is sidaguri (Sida rhombifolia). This study aims to identify the compound content of the herbal methanol extract of these species from different growing locations. Analysis of sidaguri herb methanol extracts were classified based on growing locations in Malang, Solo, Sukabumi, Tawangmangu, and Yogyakarta using liquid chromatography-mass spectrometry and grouped using principal component analysis. A total of 17 compounds were identified in the extract. These compounds are included in the phenolic group, alkaloids, steroids, flavonoids, monoterpene lactones, and amino acids and fatty acids. Fragmentation patterns were obtained for 17 compounds by means of mass spectrum fragmentation based on each compound group. The compounds contained in the samples were grouped according to their respective growth locations with a total variance of 66%. |
URI: | http://repository.ipb.ac.id/handle/123456789/111931 |
Appears in Collections: | UT - Chemistry |
Files in This Item:
File | Description | Size | Format | |
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Draft_Tugas Akhir_Ilham Alfarisi_G44170056_WM.pdf Restricted Access | Full Text | 1.88 MB | Adobe PDF | View/Open |
Abstrak_Tugas Akhir_Ilham Alfarisi_G44170056_WM.pdf Restricted Access | Abstrak | 118.59 kB | Adobe PDF | View/Open |
BAB 1_Tugas Akhir_Ilham Alfarisi_G44170056_WM.pdf Restricted Access | BAB 1 Pendahuluan | 138.07 kB | Adobe PDF | View/Open |
BAB 2_Tugas Akhir_Ilham Alfarisi_G44170056_WM.pdf Restricted Access | BAB 2 Metode | 121.64 kB | Adobe PDF | View/Open |
BAB 3_Tugas Akhir_Ilham Alfarisi_G44170056_WM.pdf Restricted Access | BAB 3 Hasil dan Pembahasan | 845.9 kB | Adobe PDF | View/Open |
BAB 4_Tugas Akhir_Ilham Alfarisi_G44170056_WM-31.pdf Restricted Access | BAB 4 Simpulan dan Saran | 115.73 kB | Adobe PDF | View/Open |
Lampiran_Tugas Akhir_Ilham Alfarisi_G44170056_WM.pdf Restricted Access | Lampiran | 986.31 kB | Adobe PDF | View/Open |
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