Echocardiography Evaluation in Piglet (Sus scrota) during Recruitment Maneuver on Pediatric Acute Lung Injury Model
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Date
2014Author
Gunanti
Nufus, Siti Khaerotun
Siswandi, Riki
Pudjladi, Antonius
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Acute lung injury (ALI) is the acute onset of bilateral infiltrate on chest radiograph without
evidence of left atrial hypertension and with a partial pressure of oxygen (Pa02)/ fraction of
inspired oxygen (FiOz) ratio of less than 300 [1]. ALI characterized by destruction of alveolarcapillary
integrity with manifestations of increased capillary permeability, non-hydrostatic
pulmonary edema. alveolar collapse. decreased lung compliance, and ventilation - perfusion
mismatch as the main cause of hypoxemia [2]. An ALI patient usually manages by mechanical
ventilation but improper use can worsen occurred lung injury, especially in children. Recent can be
handled by recruitment maneuvers.
The effectiveness of the mechanical ventilation is measured by cardiac output (CO) of the left
heart ventricle for supplying oxygen to the body [3]. Therefore, evaluation of echocardiography is
necessary. This study use piglets (Sus sero/a) as an animal model due to its similar anatomical and
physiological structure to human. ...
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