Ekstrak Jahe (Zingiber officinale Roscoe) Penghambat Oksldasl LDL
Septlana, Aisyah Tri
Zakaria, Fransisca Rungkat
MetadataShow full item record
Oxidative modifcation of DL is believed to play an importad rde in athemgenesis. DthlonnneH,ane exfmt of ginger hhomas exhibited a stmng antioxid& edivrty using lindeic acid as substrafe. We investgated the in vRro effect of these extract enkhment on the prwention of oxidative DL by CuSO* Plasma was supplemented with 43, 430, or 4300 ,ugh/ dichhethane extract in dmethykulMie (DMSO) (10 pl DMSO per ml plasma), incubated, and the UIL was $dated. Lag m e and maloneldehide conteni was anaiized a& the isdded LDL was oxidhed using CuSOc The muif showed that dth/omn?ethane extract of ginger rhizomes supkmentation prdonged lag phase tand reduced mdonddehide Ibrmdhn depended on hk c m . C m r m of 43 iMd 4300 ,ugh/ plasma of these exfract reduced msdonaldehide iunnetihn by 35,29 % and 69,72 % respectively, M not signiikenf in prdonged lag phase. Concentration of these extract with largest prolonged lag phase (82,16 %) mireduced maion&We iimnahn ( 7 4 , % was 430 ,ug!mIplasrna This research has shown that gngw extract is ctqWe of pl?decfhgDL from Oxi'dation.
- Chemistry