| dc.description.abstract | Periodontal disease included dental caries still the major problem in the world. Usually commercial tooth paste contains fluoride which has an important role to prevent tooth from damage. Cootain fluoride overdose caused fluorosis, bone damage and anemia. Therefore, the propolis was being tested as alternative additive anti caries to prevent the growth of cariogenics bacteria (Streptococcus mutans). This research studied propolis activity antibacterial and the minimum inhibitory concentration (MIC) of propolis against S. mutans. Ethanolic extract of propolis (EEP) contained various bioactive compound such as flavonoid, tannine, alkaloid, triterpenoid and saponin based on phytochemistry analyses. The extract effectivities are 96.5% relative to the propolis X, 41.04% relative to amphicillin 10 mg/ml and 240.57% relative to NaF 3000 ppm. The MIC of the extract is 3.13%. Therefore, propolis extract can be used asa additive anti caries element in tooth paste. Statistical analyses showed that 100% EEP, X propolis and amphicillin 10 mg/ml had the ability to decrease S. mutans colony | en |
