Control of Blood Glucose Level by Green Tea and or Mullberry Leaf Tea on Diabetic Rats
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Date
2008Author
Damayanthi, Evy
Efendi, Rusman
Kustiyah, Lilik
Kusumorini, Nastiti
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Antidiabetic activity of green tea (GT), mullberry leaf tea (MLT), and their mixture (GT+MLT) were evaluated in alloxan-induced diabetic rats. Blood glucose level (BGL) were measured at baselinelday-0, day-4, day-8, day-12, and day-16. Twenty five male Sprague Dawley (SD) rats aged 8 weeks were used and divided into five groups. They were) Normal rats-Water (N); Alloxan injection-Water (C); Alloxan injection-GT; Alloxan injection-MLT; Alloxan injection-GT+MLT. The dosage of treatment is 1 m1/100g body weight (BW) or equal to 100 mg polyphenol/kg BW using secondary data of polyphenol content in tea and the treatment were administered forcibly. Four groups were diabetic rats induced by alloxan intraperitoneal injection (120 mg/kg body weight (BW). The result showed that the interaction between the period of BGL measurement and I the kind of drink intervention treatment influenced BGL of diabetic rats significantly. The BGL of diabetic rats tend to decrease for treatment group, although there is not 1 significantly different between day-0 and 4. The BGL on diabetic rats of day-8, 12 and / 16 were significantly lower than the day-0 and -4.
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