Respon Sel Polimorfonuklear (PMN) Dan Makrofag Peritoneal Mencit Terhadap Streptococcus Equi Subep. Zooepidemicus

Abstract

A study on the response of mice peritoned macrophages and polymorphonucleas (PMN) cells against Streptococcus equi su bsp. zooepidernicus infection was conducted to determine the virulence of the bacteria. Encapsulated and uncapsulated bacterial cells were inoculated intrapentoneally at the dose of 10 x lo7 cells per mouse. The phagocytic activities and capacities of PMN and macrophage cells were assayed one and two hours after inoculation. The result showed an increase in the phagocytic activities of capsulated and uncapsulated bacteria. Their pbagocytic capacity declined significantly within 2 hours post inoculation. Key Words : Peritoneal macrophages, phagcqtosis, Streptococus equi subsp. zooepidernicus