Browsing by Author "Arthur M. Krieg"

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    • CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans 

      Heather L. Davis | Suparto, Irma | Weeratnaa, Risini | Jumintartod | Iskandriatic, Diah | Pawitri, Dyah | Chamzaha, Siti | Ma'rufd, Amir | Nented, Citrakasih | Pawitric, Dyah | Arthur M. Krieg | Heriyantod | Willie Smits | Sajuthi, Dondin (2010)
      Oligonucleotides containing immunostimulatory CpG motifs (CpG ODN) have been shown to be potent Th1-type adjuvants for augmenting antigen-specific responses in mice against hepatitis B surface antigen (HBsAg). The hepatitis ...

    • Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo 

      Gunther Hartmann | Risini D. Weeratna | Zuhair K. Ballas | Paul Payette | Sue Blackwell | Suparto,Irma | Wendy L. Rasmussen | Marianella Waldschmidt | Sajuthi, Dondin | Robert H. Purcell | Heather L. Davis | Arthur M. Krieg (2010)
      Oligodeoxynucleotides (ODN) containing unmethylated CpG dinucleotides within specific sequence contexts (CpG motifs) are detected, like bacterial or viral DNA, as a danger signal by the vertebrate immune system. CpG ODN ...