Suplementasi Niasin Yang Berbeda Struktur Kimia Terhadap Produktivitas Sapi Perah Laktasi: Meta-Analisis In Vivo Dan Kajian In Vitro
View/ Open
Date
2015Author
Anggreini, Rossy Endah Ayu
Laconi, Erika B.
Jayanegara, Anuraga
Metadata
Show full item recordAbstract
Niacin supplementation can inhibit the negative energy balance in dairy cows because niacin can increase microbial protein synthesis, forming an essential component of adenosine tri phosphate (ATP) and anti-lipolysis which can prevent ketosis. The present study was aimed to determine the optimum supplementation niacin, examines the effectiveness of niacin for energy balance, analyzing the effect of niacin protected against performance, productivity of lactating dairy cows (methods of meta-analysis). In this study consisted of two phases, the first phase is a study of meta-analysis and the second phase is the in vitro study. Meta-analysis using 51 articles with 30 treatment associated with supplementation of niacin which detected with scopus index. A meta-analysis using data related to the level of feed intake, nutrient digestibility and blood profiles were performed in vivo. Meta-analysis of data obtained were analyzed using SAS 9.1 and supplementation niacin in in vitro optimum at 400 ppm (resulted by meta-analysis). The in vitro study used rumen fluid from a fistulated Holstein Fresian cow obtained from Indonesian Animal Research Center, Ciawi, Bogor. The basal ration was consisted of 60% forage (grass) and 40% concentrate supplemented with niacin 400 ppm in the different chemical form of nicotinic acid (NA), niacinamide (NM), niacin protected with lipid and niacin protected with buffer agent. All samples niacin used in this study was obtained from one of the manufacturers of niacin. In vitro data analyzed using analysis of variance (ANOVA) and orthogonal contrast test to see the differences among treatments. The results of the meta-analysis showed the effect of niacin supplementation in different chemical structure can improve the digestibility of acid detergent fiber (ADF) and neutral detergent fiber digestibility (NDF), decrease the production of beta-hidroxybutyric acid (BHBA) and increase milk production. The results of in vitro study of niacin supplementation protected and not protected can not affect dry matter digestibility (DMD), organic matter digestibility (OMD), ammonia concentration, concentration of volatile fatty acids (VFA) (acetate, propionate, butyrate). In vitro study has a tendency may increase propionate concentrations and significantly increase the concentration of N-valerate. The conclusion of the study meta-analysis is the level of niacin supplementation protected and not protected at the optimum level in 400 ppm day-1 which can reduce BHBA, increases milk production. This causes the negative energy balance in lactating dairy cows can prevented. In others hand, in vitro studies of niacin supplementation had no effect on digestibility, ammonia concentration, the concentration of VFA (acetic, propionic, butyric), but can improve the concentration of N-valerate because quality of ration not correspond standar. Niacin supplementation effective if given appropriate quality standard ration.
Collections
- MT - Animal Science [1203]