Ekstraksi Propolis dan Sintesis Nanopropolis Lebah Madu Trigona spp

Abstract

Propolis is a resin adhesive material collected from worker bees from the buds, bark, and other plant parts. Propolis have many benefits are as antibacterial, aniviral, and anticancer. The purpose of this study is to search method of extraction and nanopropolis synthesis that will produce the high effectiveness, knowing antibacterial activity and knowing value of optimization nanopropolis as antibacterial against E. coli . Propolis extracted uses the method maceration with modification MAE (microwave-assisted extraction). Futhermore synthesis of nanopropolis use Aimi methode modified by high speed homogenization, hopefully nanopropolis more effective than propolis as antibacterial. The yield of propolis extract is 10.93%. The values of PSA from nanopropolis are 176.30 nm, 205.10 nm, and 295.80 nm. Result activity antibacterial nanopropolis with disc diffusion methode againts E. coli indicated nanopropolis does not have antibacterial, because nanopropolis does not produce cleare zones in disc paper area. The result from ampicilin is does not have antibacterial againts E. coli.