Dissolution behavior of ketoprofen double coted by chitosan-gum guar with alginat-CaCl2

Please use this identifier to cite or link to this item: http://repository.ipb.ac.id/handle/123456789/63969

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DC Field	Value	Language
dc.contributor.author	Sugita, Purwantiningsih
dc.contributor.author	Setyani, Yunia Anggi
dc.contributor.author	Wukirsari, Tuti
dc.contributor.author	Srijanto, Bambang
dc.date.accessioned	2013-06-04T01:42:26Z
dc.date.available	2013-06-04T01:42:26Z
dc.date.issued	2013-06-04T01:42:26Z
dc.identifier.isbn	978-979-95093-6-9
dc.identifier.uri	http://repository.ipb.ac.id/handle/123456789/63969
dc.description	Prosiding Seminar Nasional Sains III Hal.230-240	en
dc.description.abstract	Abstract : High dose ketoprofen administration as anti-inflammatory drug can cause gastrointestinal bleeding. To minimize this drawback, we have successfully double coated guar gum-modified chitosan microcapsules containing ketoprofen with alginate. The results showed that this double coating had improved the microcapsule’s stability in the gastric acid medium. The ketoprofen releasing kinetic models, both at gastric and intestinal pH, are dominated by the Korsmeyer-Peppas model suggesting that this action is following the diffusion mechanism. This kinetic model is the closest approximation to the real releasing condition.	en
dc.description.sponsorship	Fakultas MIPA – Institut Pertanian Bogor bekerja sama dengan MIPAnet	en
dc.language.iso	en
dc.relation.ispartofseries	30 Desember 2010;
dc.subject	chitosan	en
dc.subject	ketoprofen	en
dc.subject	microcapsule	en
dc.subject	dissolution	en
dc.title	Dissolution behavior of ketoprofen double coted by chitosan-gum guar with alginat-CaCl2	en
Appears in Collections:	Chemistry

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