Prenilasi Senyawa β-Diketon sebagai Prekursor 3-Prenilflavon

Please use this identifier to cite or link to this item: http://repository.ipb.ac.id/handle/123456789/62885

Full metadata record

DC Field	Value	Language
dc.contributor.advisor	Sugita, Purwantiningsih
dc.contributor.advisor	Arifin, Budi
dc.contributor.author	Sugiarto, Indra
dc.date.accessioned	2013-04-24T08:23:13Z
dc.date.available	2013-04-24T08:23:13Z
dc.date.issued	2013
dc.identifier.uri	http://repository.ipb.ac.id/handle/123456789/62885
dc.description.abstract	One group of flavonoids that has not been commonly synthesized is 3- prenylflavone. The main objective of this experiment was to synthesize precursor of 3-prenylflavone. Firstly, β-diketone was synthesized via 4 steps from phenol as starting compound with total yield of 24%. Prenylation of β-diketone with prenyl bromide and K2CO3 base produced 4 fractions which were separated by using preparative thin layer chromatography (PTLC) with n-hexane:EtOAc (8:2) as the eluent. Fraction with Rf = 0.80 was further separated by using preparative PTLC with n-hexane:EtOAc (99:1) as the eluent. Two fractions were obtained with Rf = 0.38 and 0.42. The first fraction has been characterized as diprenylated β-diketone with 49% yield. Application of protecting group on the phenolic OH group in β- diketone are needed to obtain monoprenylated β-diketone which can be further cyclized into 3-prenylflavone	en
dc.subject	Bogor Agricultural University (IPB)	en
dc.subject	synthesis	en
dc.subject	prenylation	en
dc.subject	3-prenylflavone	en
dc.subject	flavonoid	en
dc.title	Prenilasi Senyawa β-Diketon sebagai Prekursor 3-Prenilflavon	en
Appears in Collections:	UT - Chemistry

Files in This Item:

File	Description	Size	Format
G13isu.pdf Restricted Access	full text	818.78 kB	Adobe PDF	View/Open

DSpace JSPUI