Please use this identifier to cite or link to this item: http://repository.ipb.ac.id/handle/123456789/60560
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dc.contributor.advisorAchmadi, Suminar Setiati
dc.contributor.advisorArifin, Budi
dc.contributor.authorTang, Dumas Flis
dc.date.accessioned2013-02-11T01:13:11Z
dc.date.available2013-02-11T01:13:11Z
dc.date.issued2012
dc.identifier.urihttp://repository.ipb.ac.id/handle/123456789/60560
dc.description.abstractHydroxychavicolis amajorcomponentofbetel leafthat havingantibacterial, anti-inflammatory,antioxidant, anticancer, andantimutagen activities. This studyaimed tosynthesizehydroxychavicol from eugenolandsafrole. Isolation ofeugenolfromclove oilbyalkalineextraction methodgave71% yield, while theisolation ofsafrole from lawang oil byalkalineextraction method, followed by purificationusing preparative TLCgave7% yield. Eugenoldemethylationand safroledemethylenationwithAlCl3reagent weresuccessfullyproducedhydroxychavicol. The yieldswas28% and 24%, respectivelyen
dc.description.abstractHidroksikavikolmerupakankomponenutamadaunsirih yang memilikiaktivitasantibakteri, antiradang, antioksidan, antikanker, danantimutagen.Penelitianinibertujuanmenyintesissenyawatersebutdarieugenoldan darisafrol.Isolasieugenoldariminyakcengkihdenganmetodeekstraksibasamenghasil kanrendemen 71%, sedangkanisolasisafroldariminyaklawangdenganmetodeekstraksibasadilanjutkand enganpemurnianmenggunakan KLTP mendapatkanrendemen 7%. Proses demetilasiisolateugenoldandemetilenasiisolatsafroldenganpereaksi AlCl3berhasilmendapatkanprodukhidroksikavikol. Rendemen yang diperolehberturut-turut 28% dan 24%.
dc.publisherIPB ( Bogor Agricultural University )
dc.subjectdemethylationen
dc.subjectdemethylenationen
dc.subjecteugenolen
dc.subjecthydroxychavicolen
dc.subjectsafroleen
dc.titleTransformation of Eugenol and SafroleIntoHydroxychavicolen
dc.titleTransformasi Eugenol dan Safrol menjadi Hidroksikavikol
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