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Title: | Keamanan Ekstrak Etanol 96% Daun Wungu (Graptophyllum Pictum (L.) Griff) Melalui Kajian Histopat Organ Mencit. |
Authors: | Djauhari, Edy Andrianto, Dimas Setiawan., Rama Andhita |
Keywords: | Bogor Agricultural University (IPB) Ethanol 96%. Subkronis toxicity Wungu leaves |
Issue Date: | 2012 |
Abstract: | This study aims to test the safety and effect of 96% ethanol extract of leaves Wungu (Graptophyllum pictum (L.) Griff) against murine organs (liver and kidney). Security Wungu leaves tested for 3 months with subkronis toxicity methods. Grouping of experimental animals were divided into 4 groups, namely, the 100 mg / kg bb, 500 mg / kg bb, 1000 mg / kg bb and normal. The group was observed and seen the death and his body weight in treatment. Safety testing is conducted for 3 months showed that the leaf Wungu safe and beneficial in adding to the animal life. Experimental animals used in these experiments is that mice with a number of 10 fish per group. Age of mice used is 2 months. The results of death analysis produces data that can not be calculated in the LD 50 because the accretion death at the highest dose while the accretion death a little more at the lowest dose increased. Once that was done histopathologically to see the damage that occurs in the whole body. Safety testing has been conducted shows that 96% ethanol extract of leaves Wungu safe because of the death of mice used for all groups of less than 50%. When examined further conclusions based on data obtained on the histopathology of the life expectancy of mice is more in line with the addition of a large dose of a compound that is used to indicate the possibility of having the ability to increase survival of mice caused 96% ethanol extract of leaves Wungu |
URI: | http://repository.ipb.ac.id/handle/123456789/58065 |
Appears in Collections: | UT - Biochemistry |
Files in This Item:
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G12ras1.pdf Restricted Access | Full text | 1.42 MB | Adobe PDF | View/Open |
G12ras1_Abstrak.pdf Restricted Access | Abstrak | 376.72 kB | Adobe PDF | View/Open |
G12ras1_BAB I Pendahuluan.pdf Restricted Access | BAB I | 373.67 kB | Adobe PDF | View/Open |
G12ras1_BAB II Tinjauan Pustaka.pdf Restricted Access | BAB II | 502.47 kB | Adobe PDF | View/Open |
G12ras1_BAB III Bahan dan Metode.pdf Restricted Access | BAB III | 565.15 kB | Adobe PDF | View/Open |
G12ras1_BAB IV Hasil dan Pembahasan.pdf Restricted Access | BAB IV | 821.51 kB | Adobe PDF | View/Open |
G12ras1_BAB V Simpulan dan Saran.pdf Restricted Access | BAB V | 375.33 kB | Adobe PDF | View/Open |
G12ras1_Cover.pdf Restricted Access | Cover | 296.91 kB | Adobe PDF | View/Open |
G12ras1_Daftar Pustaka.pdf Restricted Access | daftar pustaka | 459.07 kB | Adobe PDF | View/Open |
G12ras1_Lampiran.pdf Restricted Access | Lampiran | 1.28 MB | Adobe PDF | View/Open |
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