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Title: | Pengaruh pemberian tepung kedelai kaya isoflavon terhadap kadar malonaldehid (mda), aktivitas superoksida dismutase (sod) testis dan profil Cu,Zn-SOD tubuli seminiferi testis tikus jantan |
Other Titles: | The effects of isoflavone-riched soybean flour on MDA Level, Superoxide dismutase (SOD) activity, and profile of Cu,Zn-superoxide dismutase(Cu,Zn-SOD) in the seminiferous tubules of male rats testes Jurnal Teknologi dan Industri Pangan Vol 20 No 2 Tahun 2009 |
Authors: | Astuti, Sussi Muchtadi, Deddy Astawan, Made Purwantara, Bambang Wresdiyati, Tutik |
Issue Date: | 2009 |
Publisher: | IPB (Bogor Agricultural University) |
Abstract: | The objectives of this experiment were to evaluate the effects of isoflavone-riched soybean flour with different treatment level of isoflavone on MDA level, SOD activity, and profile of Cu,Zn-superoxide dismutase (Cu,Zn-SOD) spermatogenic cells in the seminiferous tubules of male rat testes. Diet was given as isonitrogen and isocaloric with 10% of dietary protein. Twenty five males of Sprague Dawley rats were divided into five groups and treated with isoflavone-riched soybean flour by oral administration with different concentrations. The treatment was done for 2 months. The optimum concentration of isoflavone was 1.5 mg/day and resulted in : decreased level of MDA testes (2.29±0.05 nmol/g), mantained high SOD activity of rat testes (729.4±23.73 U/g), and increased content of Cu,Zn-SOD by immunohistochemical technique on spermatocytes and early spermatids. It was concluded that isoflavone-riched soybean flour diet (1.5 mg/day isoflavone) can prevent the formation of lipid peroxide and improve the antioxidant status of rat testes. |
URI: | http://repository.ipb.ac.id/handle/123456789/45700 |
Appears in Collections: | Jurnal Teknologi dan Industri Pangan |
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File | Description | Size | Format | |
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Jurnal Teknologi Dan Industri Pangan, Vol 20, No 2 (2009) - pengaruh pemberian tepung kedelai.doc | Abstract | 29 kB | Microsoft Word | View/Open |
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