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Title: | Quantitative Trait Loci (QTL) Analysis for Production Traits of Birth Weight and Weight 360 days in Backcross Sheep |
Other Titles: | HAYATI Journal of Biosciences Vol. 13 No.1 Tahun 2006 |
Authors: | Margawati, Endang Tri Raadsma, Herman Willem Martojo, Harimurti Subandriyo Muladno |
Issue Date: | 2006 |
Publisher: | IPB (Bogor Agricultural University) |
Series/Report no.: | Vol 13;No 1 |
Abstract: | Four half-sib families (n = 382) consisting predominantly of ITT x Merino x Merino backcross progeny, including some F2 progeny were used to analyze QTL for two production traits (Birth weight = BW1 and Body weight at 360 days = BW360). The study exploited differences in weight performance between the Merino and ITT sheep. A total of 141 informative microsatellite markers were used in a genome-wide scan covering the 26 autosomal sheep chromosomes. QTL analysis was conducted online using QTL Express. This study reports the effect of QTL for birth weight on Chromosomes 5 (p < 0.05) at 112cM (0cM-128cM). Location of candidate genes for birth weight was predicted at the region of flanking markers MCM527-BMS1247. A QTL for BW360 days existed on Chromosome 18 (p < 0.01) at 104cM (25.0-125cM). Location of candidate genes related to production traits for body weight 360 days was predicted at the segment of flanking markers of CSSM018-TMR1. Only the QTL on Chromosome 18 retained significance (p < 0.01) under experiment-wide significance testing. This QTL region is being examined for candidate genes by investigating to the homologous human chromosomal segments. |
URI: | http://repository.ipb.ac.id/handle/123456789/43279 |
ISSN: | 0854-8587 |
Appears in Collections: | Hayati Journal of Biosciences |
Files in This Item:
File | Description | Size | Format | |
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Endang Tri Margawati.pdf | e-Journal | 43.19 kB | Adobe PDF | View/Open |
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